Dr. Rynn is Chair for the Department of Psychiatry and Behavioral Sciences at Duke University School of Medicine. She is an internationally-renowned expert in the treatment of pediatric mood and anxiety disorders. She has spent her career focused on improving treatments for children, adolescents, and young adults with treatment refractory mood and anxiety disorders. Her most recent studies have examined novel augmentation treatment strategies for pediatric Obsessive-Compulsive Disorder and treatment models for adolescent depression in the primary care setting. Dr. Rynn received her medical degree from Rutgers University. She completed her internship and residency in psychiatry at the University of Pennsylvania Perelman School of Medicine and served as Chief Resident. After completing her adult psychiatry training, she completed a Child and Adolescent Psychiatry Fellowship at the Children’s Hospital of Philadelphia followed by a Neuropsychopharmacology Research Fellowship sponsored by the NIMH at the University of Pennsylvania Perelman School of Medicine. Prior to joining Columbia University, Dr. Rynn was medical director of the Mood and Anxiety Disorders Section of the Department of Psychiatry at the University of Pennsylvania Perelman School of Medicine.
Altered network connectivity predicts response to cognitive-behavioral therapy in pediatric obsessive-compulsive disorder.
Correction: Altered network connectivity predicts response to cognitive-behavioral therapy in pediatric obsessive-compulsive disorder.
Structural neural markers of response to cognitive behavioral therapy in pediatric obsessive-compulsive disorder.
The Effects of Youth Anxiety Treatment on School Impairment: Differential Outcomes Across CBT, Sertraline, and their Combination.
Primary Care: Meeting the Mental Health Care Needs of Adolescents With Depression.
Pharmacologic treatment of pediatric anxiety disordersRead Full Text
The Interplay of Familial and Individual Risk in Predicting Clinical Improvements in Pediatric Anxiety Disorders.
Secondary Outcomes From the Child/Adolescent Anxiety Multimodal Study: Implications for Clinical Practice.
Placebo Response in Pediatric Anxiety Disorders: Results from the Child/Adolescent Anxiety Multimodal Study.
Extended Release Guanfacine in Pediatric Anxiety Disorders: A Pilot, Randomized, Placebo-Controlled Trial.
21.1 COGNITIVE-BEHAVIORAL THERAPY–BASED CHANGES IN CONTROL AND REWARD CIRCUITS IN PEDIATRIC OBSESSIVE-COMPULSIVE DISORDERRead Full Text
21.0 Abnormal Neural Substrate for Performance Monitoring in Pediatric Obsessive-Compulsive Disorder: Implications for Understanding Treatment ResponseRead Full Text
Interpersonal Psychotherapy for Depression: Understanding the Core of the Interpersonal Psychotherapy for Depressed Adolescents Model and Its AdaptationsRead Full Text
47.0 Bringing Evidence-Based Treatment to Emerging Adults With Anxiety Disorders in Three Clinical Settings: The Youth Anxiety CenterRead Full Text
Trajectories of change in youth anxiety during cognitive-behavior therapy.
Predicting Anxiety Diagnoses and Severity with the CBCL-A: Improvement Relative to Other CBCL Scales?
Child/Adolescent anxiety multimodal study: evaluating safety.
Efficacy and tolerability of antidepressants in pediatric anxiety disorders: a systematic review and meta-analysis.
Parental anxiety as a predictor of medication and CBT response for anxious youth.
Web-based interventions for youth internalizing problems: a systematic review.
Somatic complaints in anxious youth.
Predictors and moderators of treatment response in childhood anxiety disorders: results from the CAMS trial.
Naturalistic follow-up of youths treated for pediatric anxiety disorders.
24- and 36-week outcomes for the Child/Adolescent Anxiety Multimodal Study (CAMS).
A probabilistic and individualized approach for predicting treatment gains: an extension and application to anxiety disordered youth.
Assessing anxiety in youth with the multidimensional anxiety scale for children.
The therapeutic relationship in cognitive-behavioral therapy and pharmacotherapy for anxious youth.
Benefits of child-focused anxiety treatments for parents and family functioning.
Therapist Factors and Outcomes in CBT for Anxiety in Youth.
Defining treatment response and remission in child anxiety: signal detection analysis using the pediatric anxiety rating scale.
Remission of generalized anxiety disorder after 6 months of open-label treatment with venlafaxine XR.
SMARTer discontinuation trial designs for developing an adaptive treatment strategy.
Psychopharmacologic treatment of children and adolescents with anxiety disorders.
Childhood anxiety: lessons learned.
Establishing the neurobiologic basis of treatment in children and adolescents with generalized anxiety disorder.
Tricyclic Antidepressants and Monoamine Oxidase Inhibitors for the Treatment of Child and Adolescent Psychiatric DisordersRead Full Text
Dr Barber and colleagues replyRead Full Text
Short-term dynamic psychotherapy versus pharmacotherapy for major depressive disorder: a randomized, placebo-controlled trial.
Remission after acute treatment in children and adolescents with anxiety disorders: findings from the CAMS.
Screening parents during child evaluations: exploring parent and child psychopathology in the same clinic.
Time to relapse after 6 and 12 months' treatment of generalized anxiety disorder with venlafaxine extended release.
Clinical characteristics of anxiety disordered youth.
Child/Adolescent Anxiety Multimodal Study (CAMS): rationale, design, and methods.
Childhood anxiety disorders: Best treatment options and practiceRead Full Text
Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety.
Attention bias toward threat in pediatric anxiety disorders.
Influence of gender on the clinical presentation of generalized anxiety disorder, and response to treatment with PregabalinRead Full Text
The varied manifestations of anxiety disorderRead Full Text
A Randomized controlled trial of venlafaxine ER versus placebo in pediatric social anxiety disorder.
Efficacy and safety of extended-release venlafaxine in the treatment of generalized anxiety disorder in children and adolescents: two placebo-controlled trials.
Social anxiety disorder in children and adolescents: epidemiology, diagnosis, and treatment.
Selegiline transdermal system for the treatment of major depressive disorder: an 8-week, double-blind, placebo-controlled, flexible-dose titration trial.
The psychometric properties of the MASC in a pediatric psychiatric sample.
Open-label pilot study of ziprasidone for refractory generalized anxiety disorder.
Generalized anxiety disorder: acute and chronic treatment.
Paroxetine in the treatment of generalised anxiety disorder.
49th Annual Meeting of the American Academy of Child & Adolescent Psychiatry. 22-27 October 2002, San Francisco, CA, USA.
Ziprasidone-associated mania: a case series and review of the mechanism.
Efficacy and safety of nefazadone in the treatment of adolescents with major depressive disorderRead Full Text
Desipramine toxicity with terbinafine.
Placebo-controlled trial of sertraline in the treatment of children with generalized anxiety disorder.
What is generalized anxiety disorder?
Assessment of Psychiatric Comorbidity in Children Infected with Human Immunodeficiency Virus, Type 1Read Full Text
Treating Pediatric Anxiety: Initial Use of SSRIs and Other Antianxiety Prescription Medications.