Faculty

Anthony Zannas

Adjunct Assistant Professor in the Department of Psychiatry and Behavioral Sciences

Psychiatry & Behavioral Sciences, Translational Neuroscience
School of Medicine

614 West Main Street, Apt 403, Durham, NC 27701

(999) 999-9999 anthony.zannas@duke.edu


Education & Training

M.D. 2004

National and Capodistrian University of Athens (Greece)

M.Sc. 2010

National and Capodistrian University of Athens (Greece)

Residency in Psychiatry, Psychiatry And Behavioral Sciences

Duke University School of Medicine

Publications

Resilience as a translational endpoint in the treatment of PTSD.

PMID 30867558
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Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk.

PMID 31113877
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Prenatal adverse environment is associated with epigenetic age deceleration at birth and hypomethylation at the hypoxia-responsive EP300 gene.

PMID 31072398
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DNA methylation levels are associated with CRF1 receptor antagonist treatment outcome in women with post-traumatic stress disorder.

PMID 30390684
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Lithium treatment and mechanisms of aging.

PMID 29422520
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Correction to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling.

PMID 29792225
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F179. Epigenetic Biomarkers in Women With Posttraumatic Stress Disorder After CRF1 Receptor Antagonist Treatment

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Gene-environment Interactions in Late Life: Linking Psychosocial Stress with Brain Aging.

PMID 29119927
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Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model.

PMID 28540928
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Aging- and Stress-Related Epigenetic Disinhibition of FKBP5 Contributes to NF-KB-Driven Inflammation and Cardiovascular Risk

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Strategies for dementia prevention: latest evidence and implications

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Comparison of two biventricular infarct patterns with respect to the infarct burden required to induce cardiogenic shock: An experimental study.

PMID 27923684
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Epigenetic programming by stress and glucocorticoids along the human lifespan.

PMID 28289275
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Life stress, glucocorticoid signaling, and the aging epigenome: Implications for aging-related diseases.

PMID 27343999
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Regulation and function of MeCP2 Ser421 phosphorylation in U50488-induced conditioned place aversion in mice.

PMID 28116477
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Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress.

PMID 27829158
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Freud and the human connectome.

PMID 27252038
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The emerging role of FKBP5 in the regulation of metabolism and body weight.

PMID 27444859
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Editorial Perspective: Psychological stress and epigenetic aging - what can we learn and how can we prevent?

PMID 27192952
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Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder.

PMID 26897419
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Heritability and reliability of automatically segmented human hippocampal formation subregions.

PMID 26747746
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FKBP51 inhibits GSK3β and augments the effects of distinct psychotropic medications.

PMID 25849320
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Genomics of PTSD

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Gene-Stress-Epigenetic Regulation of FKBP5: Clinical and Translational Implications.

PMID 26250598
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Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling.

PMID 26673150
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Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine.

PMID 26602018
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Glucocorticoid signaling drives epigenetic and transcription factors to induce key regulators of human parturition.

PMID 26508787
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Epigenetics of Posttraumatic Stress Disorder: Current Evidence, Challenges, and Future Directions.

PMID 25979620
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P.1.a.031 Lifetime stress accelerates epigenetic aging

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Selective inhibitors of the FK506-binding protein 51 by induced fit.

PMID 25436518
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Hippocampus atrophy and the longitudinal course of late-life depression.

PMID 24378256
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Association of gene variants of the renin-angiotensin system with accelerated hippocampal volume loss and cognitive decline in old age.

PMID 25124854
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P.1.a.003 Epigenetic regulation at the FKBP5 genetic locus by age and depressive phenotypes: implications for age-related disease

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Impact of ¹⁸F-florbetapir PET imaging of β-amyloid neuritic plaque density on clinical decision-making.

PMID 23672654
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The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival.

PMID 24983519
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Epigenetics and the regulation of stress vulnerability and resilience.

PMID 24333971
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Donepezil treatment of older adults with cognitive impairment and depression (DOTCODE study): clinical rationale and design.

PMID 24315979
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P.1.027 The role of FKBP5 in mechanisms linking stress and aging

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Cholinesterase inhibitors and Pisa syndrome: a pharmacovigilance study.

PMID 24127392
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Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism.

PMID 24219237
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Negative life stress and longitudinal hippocampal volume changes in older adults with and without depression.

PMID 23478048
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Change in Hippocampus Volume and Longitudinal Course of Late-Life Depression

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Phosphorylation of MeCP2 in Reward-Related Circuits is Required for Amphetamine-Induced Conditioned Place Preference in Mice

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Mechanical unloading and heart remodeling features

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Hypothalamic-pituitary-adrenal axis and cardiovascular disease

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Stressful life events, perceived stress, and 12-month course of geriatric depression: direct effects and moderation by the 5-HTTLPR and COMT Val158Met polymorphisms.

PMID 22044241
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Stressful Life Events and Two-Year Change in Hippocampal Volume in Patients with Late-Life Depression and Elderly Controls

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How much is a picture worth? Putting amyloid imaging to the test.

PMID 23341830
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