Faculty

Ashwin Patkar

Professor of Psychiatry and Behavioral Sciences

Psychiatry & Behavioral Sciences, Addiction
School of Medicine

Professor in Family Medicine and Community Health

Family Medicine and Community Health, Community Health
School of Medicine
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2213 Elba Street, Suite165, Durham, NC 27705

DUMC 3074, Durham, NC 27710

(919) 668-3626 ashwin.patkar@duke.edu


Education & Training

M.D. 1989

University of Bombay, St. Xavier College

Grants

RCT of an Integrated Treatment of Persons with Co-Occurring HCV and Alcohol Abuse

National Institutes of Health

Levomilnacipran

Pain due to Fibromyalgia in Subjects with Chronic Kidney Disease

DS-5565 in Subjects with Pain Associated with Fibromyalgia

DS-5565-E312 in Subjects with Pain Associated with Fibromyalgia

Carolinas Comprehensive Substance Abuse Services Project

Vulnerability to Drug Abuse:Pathways to Recovery

National Institutes of Health

Neurobehavioral and fMRI Research in HIV Infection and Cocaine Dependence

National Institutes of Health

A developmental model of gene-environment interplay in SUDs

National Institutes of Health

Novel Ondansetron Formulation for Combination Treatment of Psychostimulant Abuse

National Institutes of Health

Carolina Alcohol and Drug Expansion Team (CADET)

Integrated Treatment of Persons with Co-Occurring HCV and Alcohol Use/Abuse

National Institutes of Health

PREMIER Mental Health Interventions Training Program

National Institutes of Health

PARTNER

National Institutes of Health

Place of Low-Dose Naltrexone in Opiate Detoxification

National Institutes of Health

Serotonin and Cocaine Dependence

National Institutes of Health
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Publications

The Potential Utility of Aripiprazole Augmentation for Major Depressive Disorder with Mixed Features Specifier: A Retrospective Study.

PMID 31671486
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Guidance for switching from off-label antipsychotics to pimavanserin for Parkinson's disease psychosis: an expert consensus.

PMID 31182180
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Genes Involved in Neurodevelopment, Neuroplasticity and Major Depression: No Association for CACNA1C, CHRNA7 and MAPK1.

PMID 31352702
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Reduced CXCL1/GRO chemokine plasma levels are a possible biomarker of elderly depression.

PMID 30826620
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IAPA Symposium: Depression and Addictions: A complex comorbidity

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Increased plasma complement factor H is associated with geriatric depression.

PMID 29798743
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Erratum: Correction of Acknowledgements Second Generation Antipsychotics in the Treatment of Major Depressive Disorder: An Update.

PMID 30740348
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EXPLORATORY FINDINGS MAY IMPLICATE GENE'S VARIANTS, RELATED TO ANTIPSYCHOTIC MECHANISMS OF ACTION, WITH SCHIZOPHRENIA PSYCHOPATHOLOGICAL FEATURES

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Guidance for switching from off-label antipsychotics to pimavanserin for Parkinson's disease psychosis: an expert consensus.

PMID 30588905
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A Pharmacogenomic-based Antidepressant Treatment for Patients with Major Depressive Disorder: Results from an 8-week, Randomized, Single-blinded Clinical Trial.

PMID 30466219
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A pharmacogenomic-based antidepressant treatment for patients with major depressive disorder: Results from an 8-week, randomized, single-blinded clinical trial

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Neuroplasticity, Neurotransmission and Brain-Related Genes in Major Depression and Bipolar Disorder: Focus on Treatment Outcomes in an Asiatic Sample.

PMID 30178121
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The Hepatitis C-Alcohol Reduction Treatment (Hep ART) intervention: Study protocol of a multi-center randomized controlled trial.

PMID 30006024
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Addressing the Side Effects of Contemporary Antidepressant Drugs: A Comprehensive Review.

PMID 29854675
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Sickness absence indicating depressive symptoms of working population in South Korea.

PMID 29154166
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Hot Genes in Schizophrenia: How Clinical Datasets Could Help to Refine their Role.

PMID 29260453
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Efficacy of antidepressants: bias in randomized clinical trials and related issues.

PMID 28893095
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Genetic Variants Within Molecular Targets of Antipsychotic Treatment: Effects on Treatment Response, Schizophrenia Risk, and Psychopathological Features.

PMID 29164477
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CACNA1C GENE AND SCHIZOPHRENIA: A CASE CONTROL AND PHARMACOGENETIC STUDY SHORT TITLE: CACN1C GENE AND SCHIZOPHRENIA

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IMPACT OF A SINGLE NUCLEOTIDE POLYMORPHISM IN SIGMAR1 ON MAJOR DEPRESSION, BIPOLAR DISORDER AND TREATMENT RESPONSE

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GENOME-WIDE ASSOCIATION STUDY OF ANTIDEPRESSANT RESPONSE: INVOLVEMENT OF THE INORGANIC CATION TRANSMEMBRANE TRANSPORTER ACTIVITY PATHWAY

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HOT GENES IN SCHIZOPHRENIA: CASE-CONTROL, PHARMACOGENETICS AND EXPLORATORY ANALYSES IN TWO INDEPENDENT SAMPLES

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Genetic variants within key nodes of the cascade of antipsychotic mechanisms: effects on treatment response and schizophrenia psychopathology

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Comparison between long-acting injectable aripiprazole versus paliperidone palmitate in the treatment of schizophrenia: systematic review and indirect treatment comparison.

PMID 28430670
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An Item Bank for Abuse of Prescription Pain Medication from the Patient-Reported Outcomes Measurement Information System (PROMIS®).

PMID 28339555
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Investigational dopamine antagonists for the treatment of schizophrenia.

PMID 28443355
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Genetic Variants Within Key Nodes of the Cascade of Antipsychotic Mechanisms: Effects on Antipsychotic Response and Schizophrenia Psychopathology in a Naturalistic Treatment Setting in Two Independent Korean and Italian Samples.

PMID 28508933
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The Impact of a Single Nucleotide Polymorphism in SIGMAR1 on Depressive Symptoms in Major Depressive Disorder and Bipolar Disorder.

PMID 28144920
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Measurement-based Treatment of Residual Symptoms Using Clinically Useful Depression Outcome Scale: Korean Validation Study.

PMID 28138107
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Adjunctive Brexpiprazole as a Novel Effective Strategy for Treating Major Depressive Disorder: A Systematic Review and Meta-Analysis.

PMID 27941419
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Keep your patients safe: Identify patients at risk, ensure an accurate evaluation, and treat the underlying disorder

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Modafinil for the treatment of attention-deficit/hyperactivity disorder: A meta-analysis.

PMID 27810669
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A Korean validation study of the Clinically Useful Anxiety Outcome Scale: Comorbidity and differentiation of anxiety and depressive disorders.

PMID 28604808
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Hot genes in schizophrenia: case-control, pharmacogenetics and exploratory analyses in two independent samples

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Second Generation Antipsychotics in the Treatment of Major Depressive Disorder: An Update.

PMID 27689026
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Characteristics of neurocognitive functions in mild cognitive impairment with depression.

PMID 26960534
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Precision medicine for psychopharmacology: a general introduction.

PMID 27104961
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Hot genes in schizophrenia: case-control, pharmacogenetics and exploratory analyses in two independent samples

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Vilazodone for the Treatment of Depression: An Update.

PMID 27231672
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Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway.

PMID 27091189
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Corrigendum to "Item banks for substance use from the Patient-Reported Outcomes Measurement Information System (PROMIS®): Severity of use and positive appeal of use" [Drug Alcohol Depend. 156 (2015) 184-192] doi: 10.1016/j.drugalcdep.2015.09.008]

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PDE7B, NMBR and EPM2A Variants and Schizophrenia: A Case-Control and Pharmacogenetics Study.

PMID 27092952
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Genes Involved in Neurodevelopment, Neuroplasticity, and Bipolar Disorder: CACNA1C, CHRNA1, and MAPK1.

PMID 28494468
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Item banks for substance use from the Patient-Reported Outcomes Measurement Information System (PROMIS(®)): Severity of use and positive appeal of use.

PMID 26423364
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P.1.a.015 Brain-Derived Neurotrophic Factor (BDNF) genetic pathway and bipolar disorder

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P1.a.023 Impact of a SNP in SIGMAR1 on major depression, bipolar disorder and treatment response

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P.1.a.006 CACNA1C gene and schizophrenia: A case-control and pharmacogenetic study

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CACNA1C gene and schizophrenia: a case-control and pharmacogenetic study.

PMID 26049408
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Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood.

PMID 26081443
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A 13-week, randomized double-blind, placebo-controlled, cross-over trial of ziprasidone in bipolar spectrum disorder.

PMID 25882763
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Fibromyalgia diagnosis: a review of the past, present and future.

PMID 26035624
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Vortioxetine: a meta-analysis of 12 short-term, randomized, placebo-controlled clinical trials for the treatment of major depressive disorder.

PMID 25350320
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Vortioxetine, a multimodal antidepressant for generalized anxiety disorder: a systematic review and meta-analysis.

PMID 25851751
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Vilazodone for the treatment of major depressive disorder: focusing on its clinical studies and mechanism of action.

PMID 25866514
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Curcumin as a putative antidepressant.

PMID 25644944
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The influence of AHI1 variants on the diagnosis and treatment outcome in schizophrenia.

PMID 25622261
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Quetiapine augmentation for depression: dosing pattern in routine practice.

PMID 25371174
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Five potential therapeutic agents as antidepressants: a brief review and future directions.

PMID 26312645
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An 8-Week Randomized, Double-Blind Trial Comparing Efficacy, Safety, and Tolerability of 3 Vilazodone Dose-Initiation Strategies Following Switch From SSRIs and SNRIs in Major Depressive Disorder.

PMID 26693034
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Usefulness of the Patient Health Questionnaire-9 for Korean medical students.

PMID 24804631
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Abelson helper integration site-1 gene variants on major depressive disorder and bipolar disorder.

PMID 25395981
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Preclinical pharmacology of amphetamine: implications for the treatment of neuropsychiatric disorders.

PMID 24657455
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The potential role of atypical antipsychotics for the treatment of posttraumatic stress disorder.

PMID 24882700
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Efficacy and safety of selegiline transdermal system (STS) for the atypical subtype of major depressive disorder: pooled analysis of 5 short-term, placebo-controlled trials.

PMID 24168807
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A review of current evidence for acetyl-l-carnitine in the treatment of depression.

PMID 24607292
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Lack of influence of rs4680 (COMT) and rs6276 (DRD2) on diagnosis and clinical outcomes in patients with major depression.

PMID 24555772
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Epistatic Interactions between CREB and CREM Variants in Affective Disorder.

PMID 24843377
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Aripiprazole augmentation for major depressive disorder: dosing patterns in a naturalistic treatment setting.

PMID 24108149
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Substance Use Outcomes of an Integrated HIV-Substance Use Treatment Model Implemented by Social Workers and HIV Medical Providers

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Antidepressant and QT interval prolongation, how should we look at this issue? Focus on citalopram.

PMID 24131458
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Schizophrenia relapse and the clinical usefulness of once-monthly aripiprazole depot injection

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Substance Use disorder in DSM-V: Revisions and Rationale: IAPA Symposium, USA

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International prescribing patterns for mood illness: the International Mood Network (IMN).

PMID 24955565
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Schizophrenia relapse and the clinical usefulness of once-monthly aripiprazole depot injection.

PMID 25210454
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A double-blind, placebo-controlled, parallel-group pilot study of milnacipran for chronic radicular pain (sciatica) associated with lumbosacral disc disease.

PMID 25664215
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Predictors of relapse in patients with major depressive disorder in a 52-week, fixed dose, double blind, randomized trial of selegiline transdermal system (STS).

PMID 24021959
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Buprenorphine implants for treatment of opioid dependence: randomized comparison to placebo and sublingual buprenorphine/naloxone.

PMID 23919595
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Asenapine, blonanserin, iloperidone, lurasidone, and sertindole: distinctive clinical characteristics of 5 novel atypical antipsychotics.

PMID 24201235
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Oxidative/nitrosative stress and antidepressants: targets for novel antidepressants.

PMID 23022673
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Sensitivity of cognitive tests in four cognitive domains in discriminating MDD patients from healthy controls: a meta-analysis.

PMID 23725644
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Medication for Cravings in Substance Use Disorders

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Case-control association study of 36 single-nucleotide polymorphisms within 10 candidate genes for major depression and bipolar disorder.

PMID 23273899
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A review of current evidence for vilazodone in major depressive disorder.

PMID 23578403
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A randomized controlled trial of the efficacy and safety of lisdexamfetamine dimesylate as augmentation therapy in adults with residual symptoms of major depressive disorder after treatment with escitalopram.

PMID 24021497
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Second-generation antipsychotics in the treatment of major depressive disorder: current evidence.

PMID 23898855
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Dilemma for enhancing psychiatrists' adherence to guideline (evidence)-based practice.

PMID 23898847
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Investigation of possible epistatic interactions between GRIA2 and GRIA4 variants on clinical outcomes in patients with major depressive disorder.

PMID 23613500
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Lisdexamfetamine Dimesylate Augmentation Effects on Executive Function in Major Depressive Disorder Based on Level of Executive Function Impairment

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Atypical antipsychotics as a possible treatment option for irritable bowel syndrome.

PMID 23506326
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Clinical issues in use of atypical antipsychotics for depressed patients.

PMID 23709360
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Atypical antipsychotic augmentation strategies in the context of guideline-based care for the treatment of major depressive disorder.

PMID 23709359
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Vitamin D deficiency and psychiatric illness

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Genes, environments, and developmental research: methods for a multi-site study of early substance abuse.

PMID 23461817
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Effects of milnacipran on neurocognition, pain, and fatigue in fibromyalgia: a 13-week, randomized, placebo-controlled, crossover trial.

PMID 24800123
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P.2.c.012 Predictors of response and remission during an open-label, 10-week trial with selegiline transdermal system

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P.2.c.013 Efficacy and safety of selegiline transdermal system for atypical depression: pooled analysis of short-term placebo-controlled trials

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Attitudes on clinical research participation of community living elders in Korea

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Predictors of attrition with buprenorphine/naloxone treatment in opioid dependent youth.

PMID 22626890
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Paliperidone: a review of clinical trial data and clinical implications.

PMID 22747259
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Pharmacologically-mediated reactivation and reconsolidation blockade of the psychostimulant-abuse circuit: a novel treatment strategy.

PMID 22356892
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Efficacy and safety of lisdexamfetamine dimesylate as augmentation therapy in adults with major depressive disorder treated with an antidepressant

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Case-control association study of 14 variants of CREB1, CREBBP and CREM on diagnosis and treatment outcome in major depressive disorder and bipolar disorder.

PMID 22386572
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Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder.

PMID 22057216
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Predictors of response to ziprasidone: results from a 6-week randomized double-blind, placebo-controlled trial for acute depressive mixed state.

PMID 22294238
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The combination very low-dose naltrexone-clonidine in the management of opioid withdrawal.

PMID 22233189
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Safety of selegiline transdermal system in clinical practice: analysis of adverse events from postmarketing exposures.

PMID 22697192
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Selegiline transdermal system in major depressive disorder

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An integrated alcohol abuse and medical treatment model for patients with hepatitis C.

PMID 22134784
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Case-control association study for 10 genes in patients with schizophrenia: influence of 5HTR1A variation rs10042486 on schizophrenia and response to antipsychotics.

PMID 22120873
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Case-control association study of GRIA1, GRIA2 and GRIA4 polymorphisms in bipolar disorder.

PMID 22122651
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Possible influence of CREB1, CREBBP and CREM variants on diagnosis and treatment outcome in patients with schizophrenia.

PMID 22198373
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Association of chronic divalproex sodium use and brain atrophy in Alzheimer's disease.

PMID 22288670
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Mixed depression: a study of its phenomenology and relation to treatment response.

PMID 22173265
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A 6 week randomized double-blind placebo-controlled trial of ziprasidone for the acute depressive mixed state.

PMID 22545088
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Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia.

PMID 22094384
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DAOA variants on diagnosis and response to treatment in patients with major depressive disorder and bipolar disorder.

PMID 22429365
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Influence of BDNF variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia.

PMID 22094229
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DAOA variants and schizophrenia: influence on diagnosis and treatment outcomes.

PMID 22122005
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Aripiprazole treatment for patients with schizophrenia: from acute treatment to maintenance treatment.

PMID 22014131
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Escitalopram for the treatment of major depressive disorder in youth.

PMID 21895554
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Influence of TPH2 variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia.

PMID 21396719
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Available therapies and current management of fibromyalgia: focusing on pharmacological agents.

PMID 22013561
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Problem drinking and low-dose naltrexone-assisted opioid detoxification.

PMID 21513688
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A national epidemic of unintentional prescription opioid overdose deaths: how physicians can help control it.

PMID 21536000
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A retrospective comparison of BMI changes and the potential risk factors among schizophrenic inpatients treated with aripiprazole, olanzapine, quetiapine or risperidone.

PMID 21146575
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Association of sedative-hypnotic medications with suicidality.

PMID 21375440
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Aripiprazole as adjunctive therapy for patients with major depressive disorder: overview and implications of clinical trial data.

PMID 21254788
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Safety and tolerability of lamotrigine: results from 12 placebo-controlled clinical trials and clinical implications.

PMID 21242744
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TAAR6 variations possibly associated with antidepressant response and suicidal behavior.

PMID 20493543
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Armodafinil as adjunctive therapy in adults with cognitive deficits associated with schizophrenia: a 4-week, double-blind, placebo-controlled study.

PMID 20816042
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Buprenorphine implants for treatment of opioid dependence: a randomized controlled trial.

PMID 20940383
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Quetiapine XR: current status for the treatment of major depressive disorder.

PMID 20307622
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HIV risk behavior in treatment-seeking opioid-dependent youth: results from a NIDA clinical trials network multisite study.

PMID 20393347
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No influence of SLC6A3 40 base VNTR polymorphism on the response to risperidone.

PMID 24917325
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Reduced cannabis use after low-dose naltrexone addition to opioid detoxification.

PMID 20631574
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Treatments for alcohol dependence: rethinking the role of comorbidity and clinical subtypes.

PMID 20516159
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Investigation of an epistastic effect between a set of TAAR6 and HSP-70 genes variations and major mood disorders.

PMID 19582769
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Paroxetine mesylate: comparable to paroxetine hydrochloride?

PMID 20088740
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Predictors of early worsening after switch to aripiprazole: a randomized, controlled, open-label study.

PMID 20155991
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Desvenlafaxine succinate: a newer antidepressant for the treatment of depression and somatic symptoms.

PMID 20107296
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Opioid use affects antioxidant activity and purine metabolism: preliminary results.

PMID 19760630
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Serotonin-norepinephrine reuptake inhibitors for pain control: premise and promise.

PMID 20514212
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Atypical depression: a comprehensive review.

PMID 19958040
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Milnacipran: beyond a role of antidepressant.

PMID 19620845
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Epistasis between a set of variations located in the TAAR6 and HSP-70 genes toward schizophrenia and response to antipsychotic treatment.

PMID 19643584
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Psychometric properties of the Patient Health Questionnaire-15 (PHQ-15) for measuring the somatic symptoms of psychiatric outpatients.

PMID 19996228
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Alterations in tryptophan and purine metabolism in cocaine addiction: a metabolomic study.

PMID 19649617
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History of depressive and/or anxiety disorders as a predictor of treatment response: a post hoc analysis of a 12-week, randomized, double-blind, placebo-controlled trial of paroxetine controlled release in patients with fibromyalgia.

PMID 19433129
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The construct and measurement equivalence of cocaine and opioid dependences: a National Drug Abuse Treatment Clinical Trials Network (CTN) study.

PMID 19423244
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The high prevalence of substance use disorders among recent MDMA users compared with other drug users: Implications for intervention.

PMID 19361931
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Association of MDMA/ecstasy and other substance use with self-reported sexually transmitted diseases among college-aged adults: a national study.

PMID 19656538
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Pharmacological treatment of chronic fatigue syndrome: focusing on the role of antidepressants.

PMID 19514866
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Does pregabalin have neuropsychotropic effects?: a short perspective.

PMID 20046375
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Thyroid hormones affect recovery from depression during antidepressant treatment.

PMID 19566761
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An item response theory modeling of alcohol and marijuana dependences: a National Drug Abuse Treatment Clinical Trials Network study.

PMID 19371493
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Heterogeneity of stimulant dependence: a national drug abuse treatment clinical trials network study.

PMID 19340639
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Very low dose naltrexone addition in opioid detoxification: a randomized, controlled trial.

PMID 18715283
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Dysbindin gene (DTNBP1) and schizophrenia in Korean population.

PMID 19252939
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Short-, intermediate-, and long-term outcomes of Pennsylvania's continuum of tobacco education pilot project.

PMID 19351786
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Effects of Adjunctive Armodafinil on Patients with Schizophrenia

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EFFICACY AND TOLERABILITY OF ADJUNCTIVE ARMODAFINIL IN PATIENTS WITH SCHIZOPHRENIA

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Early outcomes following low dose naltrexone enhancement of opioid detoxification.

PMID 19283561
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The impact of the CONSORT statement on reporting of randomized clinical trials in psychiatry.

PMID 19070681
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Methylphenidate extended release (OROS MPH) for the treatment of antidepressant-related sexual dysfunction in patients with treatment-resistant depression: results from a 4-week, double-blind, placebo-controlled trial.

PMID 19512961
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Effectiveness of antidepressant treatments in pre-menopausal versus post-menopausal women: a pilot study on differential effects of sex hormones on antidepressant effects.

PMID 18502089
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Augmentation of dopaminergic agents for major depressive disorder.

PMID 19317962
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Childhood abuse and treatment response in patients with irritable bowel syndrome: a post-hoc analysis of a 12-week, randomized, double-blind, placebo-controlled trial of paroxetine controlled release.

PMID 19125906
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Corrigendum to: "TAAR6 variation effect on clinic presentation and outcome in a sample of schizophrenic in-patients: An open label study" [Eur Psychiatr 2008;23:390-5] (DOI:10.1016/j.eurpsy.2008.04.004)

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A double-blind, randomized, placebo-controlled trial of paroxetine controlled-release in irritable bowel syndrome.

PMID 19213976
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Pregabalin augmentation of antidepressants in patients with accident-related posttraumatic stress disorder: an open label pilot study.

PMID 19060720
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Desvenlafaxine, a serotonin-norepinephrine uptake inhibitor for major depressive disorder, neuropathic pain and the vasomotor symptoms associated with menopause.

PMID 19127490
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Duloxetine: an emerging evidence for fibromyalgia.

PMID 18502090
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Sodium oxybate relieves pain and improves function in fibromyalgia syndrome: a randomized, double-blind, placebo-controlled, multicenter clinical trial.

PMID 19116896
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History of early abuse as a predictor of treatment response in patients with fibromyalgia: a post-hoc analysis of a 12-week, randomized, double-blind, placebo-controlled trial of paroxetine controlled release.

PMID 19382010
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Corrigendum to "DTNBP1 haplotype influences baseline assessment scores of schizophrenic in-patients" [Neurosci. Lett. 440 (2008) 150-154] (DOI:10.1016/j.neulet.2008.05.069)

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HSP70 variations in the acute treatment with mood stabilizers in patients with bipolar disorder: Results of a preliminary work

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Triple reuptake inhibitors: the next generation of antidepressants.

PMID 19587855
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Extended vs short-term buprenorphine-naloxone for treatment of opioid-addicted youth: a randomized trial.

PMID 18984887
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Paroxetine: safety and tolerability issues.

PMID 18983224
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Does neurotropin-3 have a therapeutic implication in major depression?

PMID 18853330
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Relationship of the serotonin transporter with prolactin response to meta-chlorophenylpiperazine in cocaine dependence.

PMID 18321529
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Hallucinogen use disorders among adult users of MDMA and other hallucinogens.

PMID 18770077
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Prescription pain reliever abuse and dependence among adolescents: a nationally representative study.

PMID 18664996
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Triple reuptake inhibitors: a premise and promise.

PMID 20046357
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Potential role of pregabalin in the treatment of lithium-induced tremor: a case report.

PMID 18394207
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Delirium: underrecognized and undertreated.

PMID 18782511
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TAAR6 variation effect on clinic presentation and outcome in a sample of schizophrenic in-patients: an open label study.

PMID 18583103
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DTNBP1 haplotype influences baseline assessment scores of schizophrenic in-patients.

PMID 18562100
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The relationship between fibromyalgia and major depressive disorder: a comprehensive review.

PMID 18606054
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Do estradiol levels influence on the cognitive function during antidepressant treatments in post-menopausal women with major depressive disorder? A comparison with pre-menopausal women.

PMID 18766158
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Effectiveness of antidepressant treatments in pre-menopausal versus post-menopausal women: A pilot study on differential effects of sex hormones on antidepressant effects

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Pharmacogenctic of DTNBP1 variations in the bipolar acute treatment with mood stabilizers

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DBNDD1, HSPs and TAAR6 variations influence schizophrenic phenotype and treatment response

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Infrequent illicit methadone use among stimulant-using patients in methadone maintenance treatment programs: a national drug abuse treatment clinical trials network study.

PMID 18612886
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Delirium: where do we stand?

PMID 18652793
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Paroxetine for patients with undifferentiated somatoform disorder: A prospective, open-label, 8-week pilot study.

PMID 24692800
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Does minocycline have antidepressant effect?

PMID 18267354
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Effect of the dysbindin gene on antimanic agents in patients with bipolar I disorder.

PMID 20046352
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A case of transient hallucination with ropinirole augmentation antidepressant in a patient with treatment-resistant depression: Is there differential effect of ropinirole dose on developing psychotic symptom?

PMID 18384925
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Non-prescribed use of pain relievers among adolescents in the United States.

PMID 18054444
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Comments on "Addition of lamotrigine to valproic acid: a successful outcome in a case of rapid-cycling bipolar affective disorder".

PMID 18061327
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Is there protective haplotype of dysbindin gene (DTNBP1) 3 polymorphisms for major depressive disorder.

PMID 17964051
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Fluoxetine versus sertraline in the treatment of patients with undifferentiated somatoform disorder: a randomized, open-label, 12-week, parallel-group trial.

PMID 17950970
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Reply to Dr Ng's comments on "A Randomized, Double-Blind, Placebo-Controlled Trial of Augmentation with An Extended Release Formulation of Methylphenidate in Outpatients with Treatment-Resistant Depression" [11]

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Aripiprazole in the treatment of depressive and anxiety disorders: a review of current evidence.

PMID 18399707
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The implementation of buprenorphine/naloxone in college health practice.

PMID 18316282
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The atypical antipsychotics olanzapine and risperidone in the treatment of posttraumatic stress disorder: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials.

PMID 18090502
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Association of the trace amine associated receptor 6 (TAAR6) gene with schizophrenia and bipolar disorder in a Korean case control sample.

PMID 17097106
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An open-label, rater-blinded, flexible-dose, 8-week trial of escitalopram in patients with major depressive disorder with atypical features.

PMID 18615172
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History of depressive and anxiety disorders and paroxetine response in patients with irritable bowel syndrome: post hoc analysis from a placebo-controlled study.

PMID 19158975
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Venlafaxine versus mirtazapine in the treatment of undifferentiated somatoform disorder: a 12-week prospective, open-label, randomized, parallel-group trial.

PMID 18345715
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Polypharmacy in pregnant women with major psychiatric illness: a pilot study.

PMID 18032983
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Telephone enhancement of long-term engagement (TELE) in continuing care for substance abuse treatment: a NIDA clinical trials network (CTN) study.

PMID 18058417
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Effectiveness of low-dose naltrexone in the post-detoxification treatment of opioid dependence.

PMID 17873678
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Long-acting injectable naltrexone for the treatment of alcohol dependence.

PMID 17939765
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Fatigue as a core symptom in major depressive disorder: overview and the role of bupropion.

PMID 17939764
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Irritable bowel syndrome in psychiatric perspectives: a comprehensive review.

PMID 17877658
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Quinone oxidoreductase (NQO1) gene polymorphism may not confer a susceptibility to mood disorders.

PMID 17644186
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Manganese superoxide dismutase (MnSOD: Ala-9Val) gene polymorphism may not be associated with schizophrenia and tardive dyskinesia.

PMID 17582511
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Selegiline transdermal system: current awareness and promise.

PMID 17614182
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Usefulness of long-acting injectable risperidone during 12-month maintenance therapy of bipolar disorder.

PMID 17532106
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Effect of 5-haplotype of dysbindin gene (DTNBP1) polymorphisms for the susceptibility to bipolar I disorder.

PMID 17192893
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Trends in nonheroin opioid abuse admissions: 1992-2004.

PMID 17957981
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Heat-shock protein-70 genes and response to antidepressants in major depression.

PMID 17428599
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Reduction in methamphetamine induced sensitization and reinstatement after combined pergolide plus ondansetron treatment during withdrawal.

PMID 17408614
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Transdermal selegiline

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Recent advances in poststroke depression.

PMID 17521519
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Extended-release formulation of venlafaxine in the treatment of post-traumatic stress disorder.

PMID 17563244
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Transdermal selegiline.

PMID 17612708
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A randomized, controlled, trial of controlled release paroxetine in fibromyalgia

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A randomized, controlled, trial of controlled release paroxetine in fibromyalgia.

PMID 17466657
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Erratum: Paroxetine: Current status in psychiatry (Expert Review of Neurotherapeutics (2007) 7, 2, (107-120))

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Rapid versus conventional initiation of quetiapine in the treatment of schizophrenia: a randomized, parallel-group trial.

PMID 17388709
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Paroxetine: current status in psychiatry.

PMID 17286545
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Dysbindin associated with selective serotonin reuptake inhibitor antidepressant efficacy.

PMID 17264804
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Aripiprazole augmentation for treatment of patients with inadequate antidepressants response.

PMID 17111388
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Buprenorphine treatment: factors and first-hand experiences for providers to consider.

PMID 17439863
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A randomized, double-blind, placebo-controlled trial of augmentation with an extended release formulation of methylphenidate in outpatients with treatment-resistant depression.

PMID 17110825
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Polymorphism in the serotonin transporter gene and moderators of prolactin response to meta-chlorophenylpiperazine in African-American cocaine abusers and controls.

PMID 17000009
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Dysbindin associated with SSRI antidepressant efficacy

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Adjunctive risperidone, olanzapine and quetiapine for the treatment of hospitalized patients with bipolar I disorder: a retrospective study.

PMID 16631294
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Manganese superoxide dismutase (MnSOD: Ala-9Val) gene polymorphism and mood disorders: a preliminary study.

PMID 16626843
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Relationship of prolactin response to meta-chlorophenylpiperazine with severity of drug use in cocaine dependence.

PMID 16915581
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A randomized, double-blind, placebo-controlled, flexible-dose, trial of augmentation with OROS methylphenidate in Treatment Resistant Depression

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A comparison of tolerability profiles of patients with major depressive disorder receiving selective serotonin reputake inhibitors (SSRIS) in a naturalistic clinical care setting.

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Effectiveness of escitalopram vs venlafaxine XR in major depression in a real world clinical setting

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A randomized, double-blind, placebo-controlled trial of sodium oxybate in fibromyalgia syndrome [FMS]

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A randomized, placebo-controlled, double-blind trial of paroxetine controlled release (CR) in irritable bowel syndrome

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Transdermal selegiline: the new generation of monoamine oxidase inhibitors.

PMID 16641841
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Relationship of disinhibition and aggression to blunted prolactin response to meta-chlorophenylpiperazine in cocaine-dependent patients.

PMID 16418827
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Clinical variables associated with early administration of antipsychotics in bipolar mania.

PMID 16253411
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Changes in tobacco smoking following treatment for cocaine dependence.

PMID 16595320
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An open-label, rater-blinded, augmentation study of aripiprazole in treatment-resistant depression.

PMID 16862232
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Polypharmacy in schizophrenia.

PMID 24941144
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Paroxetine for somatic pain associated with physical illness: a review.

PMID 16912814
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A randomized, double-blind, placebo-controlled, flexible-dose, trial of augmentation with oros methylphenidate in treatment resistant depression

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A functional prodynorphin promoter polymorphism and opioid dependence.

PMID 16314761
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The relationship between nicotine dependence and addiction severity amongst cocaine abusers

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Polymorphism in the serotonin transporter gene and response to treatment in African American cocaine and alcohol-abusing individuals.

PMID 16109588
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Randomized, placebo-controlled, double-blind trial of paroxetine controlled release in irritable bowel syndrome

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Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence.

PMID 15558714
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Medical symptoms associated with tobacco smoking with and without marijuana abuse among crack cocaine-dependent patients.

PMID 15804876
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Safety considerations in pharmacotherapy of bipolar disorder

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Safety considerations in pharmacotherapy of bipolar disorder.

PMID 15529089
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Safety Considerations in Pharmacotherapy of Bipolar Disorder

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Relationship of serum prolactin with severity of drug use and treatment outcome in cocaine dependence.

PMID 15064918
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P.3.037 A randomized, double-blind, placebo-controlled trial: Paroxetine controlled release in fibromyalgia

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Paroxetine CR (paxil CR) in the treatment of patients with fibromyalgia: A randomized, double blind, parallel group, flexible dose, placebo-controlled trial

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Randomized, placebo-controlled, double-blind trial of paroxetine controlled release in irritable bowel syndrome

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Psychotic symptoms in patients with medical disorders.

PMID 15142475
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Differences in peripheral noradrenergic function among actively drinking and abstinent alcohol-dependent individuals.

PMID 15370942
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Pharmacotherapy of depression in pregnancy.

PMID 15328902
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Relationship between serotonin transporter gene polymorphisms and platelet serotonin transporter sites among African-American cocaine-dependent individuals and healthy volunteers.

PMID 15091312
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Comparison of pretreatment characteristics and treatment outcomes for alcohol-, cocaine-, and multisubstance-dependent patients.

PMID 15077843
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Pre-treatment measures of impulsivity, aggression and sensation seeking are associated with treatment outcome for African-American cocaine-dependent patients.

PMID 15132346
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ACGME research requirements for residents in psychiatry.

PMID 15673836
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Relationship of Aggression, Sensation Seeking, and Impulsivity, with Severity of Cocaine Use

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A comparison of smoking habits among medical and nursing students.

PMID 14555574
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Relationship between platelet serotonin uptake sites and measures of impulsivity, aggression, and craving among African-American cocaine abusers.

PMID 14660157
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Fluvoxamine as an adjunct to promote methadone dose optimization

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A genetic association study of the mu opioid receptor and severe opioid dependence

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A genetic association study of the mu opioid receptor and severe opioid dependence.

PMID 12960749
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High- and low-structure treatments for substance dependence: role of learned helplessness.

PMID 14510041
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Management of fibromyalgia.

PMID 12773276
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Nicotine dependence and treatment outcome among African American cocaine-dependent patients.

PMID 12791537
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Changes in plasma noradrenaline and serotonin levels and craving during alcohol withdrawal.

PMID 12711656
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The genetic determinants of smoking.

PMID 12740294
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Twenty-first century tobacco use: it is not just a risk factor anymore.

PMID 12693789
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Seasonal variations in the binding of [3H]paroxetine to the platelet serotonin transporter sites in African-American cocaine-dependent patients and healthy volunteers.

PMID 12590403
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Differences in platelet serotonin transporter sites between African-American tobacco smokers and non-smokers.

PMID 12589524
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Disturbances in serotonergic function among cocaine abusers

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Coping styles and response to high versus low-structure individual counseling for substance abuse.

PMID 12623738
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Tobacco smoking: current concepts in etiology and treatment.

PMID 14587355
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Relationship between platelet serotonin uptake sites and treatment outcome among African-American cocaine dependent individuals.

PMID 12661981
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Relationship between tobacco smoking and positive and negative symptoms in schizophrenia

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No association between polymorphisms in the serotonin transporter gene and susceptibility to cocaine dependence among African-American individuals.

PMID 12218660
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Tobacco smoking as a chronic disease: notes on prevention and treatment.

PMID 12529902
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Relationship between tobacco smoking and positive and negative symptoms in schizophrenia.

PMID 12357094
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Public health implications of voters' attitudes regarding statewide tobacco policy.

PMID 12114373
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Predicting treatment-outcome in cocaine dependence from admission urine drug screen and peripheral serotonergic measures.

PMID 12127466
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Serotonin transporter polymorphisms and measures of impulsivity, aggression, and sensation seeking among African-American cocaine-dependent individuals.

PMID 12057823
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Tobacco and alcohol use and medical symptoms among cocaine dependent patients.

PMID 12444355
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Changes in mu opioid receptors and rheological properties of erythrocytes among opioid abusers.

PMID 12006216
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Predicting treatment-outcome of cocaine-dependent patients from baseline urine drug screen and platelet paroxetine binding

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Relationship between tobacco smoking and medical symptoms among cocaine-, alcohol-, and opiate-dependent patients.

PMID 12202013
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Serum prolactin and response to treatment among cocaine-dependent individuals.

PMID 11900622
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Serotonin transporter (5-HTT) gene polymorphisms and susceptibility to cocaine dependence among African-American individuals.

PMID 11900612
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Red blood cell abnormalities among opiate abusers

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ECT in the presence of brain tumor and increased intracranial pressure: evaluation and reduction of risk.

PMID 10868329
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Elevated mu opioid receptor densities on blood cells from opiate abusers

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Smoking among medical students: Comparison across class years

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A Comparison of Medical Symptoms Reported by Cocaine-, Opiate-, and Alcohol-Dependent Patients.

PMID 12511830
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3. ECT in the Presence of Brain Tumor and Increased Intracranial Pressure

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Cigarette smoking and medical symptoms among cocaine abusers.

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Changing patterns of illicit substance use among schizophrenic patients: 1984-1996.

PMID 10189516
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Comparison of hair analysis, urine analysis, and self-report in a cocaine treatment outcome study

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Cigarette smoking and medical symptoms among opiate, cocaine and alcohol abusers

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Schizencephaly associated with psychosis.

PMID 9328256
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Neurosyphilis occurring in a patient with schizophrenia: a cautionary tale.

PMID 9048706
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Treating delirium among elderly patients.

PMID 9117499
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Parotid gland swelling with clozapine.

PMID 8909338
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[3H]Imipramine binding in type I and type II alcoholism

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Drug misusers in police custody.

PMID 7837206
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Neuroleptic malignant syndrome (a case report).

PMID 1784031
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Pre-pubertal bipolar disorder with rapid cycles- a case report.

PMID 21927475
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Pre-pubertal bipolar disorder with 30-day spontaneous, classic, rapid cycles.

PMID 21927435
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Tertiary syphilis presenting as manic depressive psychosis.

PMID 21927396
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Updates on Preclinical and Translational Neuroscience of Mood Disorders: A Brief Historical Focus on Ketamine for the Clinician.

PMID 31688400
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