Box 3918 Med Ctr, Durham, NC 27710
Brain Imaging Analy Ctr, Hock Plaza, Room 5158, Durham, NC 27710
Research in my lab is focused on brain changes associated with posttraumatic stress disorder (PTSD), traumatic brain injury (TBI), and other neuropsychiatric disorders. We apply several advanced methods for understanding brain function including functional MRI, structural MRI, diffusion tensor imaging, and genetic effects.
The genetic architecture of the human cerebral cortex.
Combat exposure, posttraumatic stress disorder, and head injuries differentially relate to alterations in cortical thickness in military Veterans.
The role of the dentate gyrus in stress-related disorders.
A Pilot Study of Neurocognitive Function and Brain Structures in Adolescents With Alcohol Use Disorders: Does Maltreatment History Matter?
Resilience as a translational endpoint in the treatment of PTSD.
Pain Intensity and Pain Interference in Male and Female Iraq/Afghanistan-era Veterans.
Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder: A Mendelian Randomization Study.
Brain structural covariance network centrality in maltreated youth with PTSD and in maltreated youth resilient to PTSD.
Resting-state brain fluctuation and functional connectivity dissociate moral injury from posttraumatic stress disorder.
Adaptive Identification of Cortical and Subcortical Imaging Markers of Early Life Stress and Posttraumatic Stress Disorder.
Relationship between traumatic brain injury history and recent suicidal ideation in Iraq/Afghanistan-era veterans.
108. Hippocampal Subfield Volumes Relate to Unique Phenotypes of PTSD: International Analysis by the PGC-ENIGMA PTSD Working GroupRead Full Text
Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry.
Current progress and future direction in the genetics of PTSD: Focus on the development and contributions of the PGC-PTSD working groupRead Full Text
The association of resilience on psychiatric, substance use, and physical health outcomes in combat trauma-exposed military service members and veterans.
Widespread Cortical Thickness Is Associated With Neuroactive Steroid Levels.
Behavioral and Health Outcomes Associated With Deployment and Nondeployment Acquisition of Traumatic Brain Injury in Iraq and Afghanistan Veterans.
Smaller hippocampal CA1 subfield volume in posttraumatic stress disorder.
Informing Federal Policy on Firearm Restrictions for Veterans with Fiduciaries: Risk Indicators in the Post-Deployment Mental Health Study.
The Association Between Alcohol Consumption, Lifetime Alcohol Use Disorder, and Psychiatric Distress Among Male and Female Veterans.
White matter abnormalities in mild traumatic brain injury with and without post-traumatic stress disorder: a subject-specific diffusion tensor imaging study.
ENIGMA military brain injury: A coordinated meta-analysis of diffusion MRI from multiple cohortsRead Full Text
Genomic Approaches to Posttraumatic Stress Disorder: The Psychiatric Genomic Consortium Initiative.
Risk factors for concurrent suicidal ideation and violent impulses in military veterans.
Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.
Structural covariance network centrality in maltreated youth with posttraumatic stress disorder.
Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia.
Multi-site harmonization of diffusion MRI data in a registration framework.
White Matter Changes Related to Subconcussive Impact Frequency during a Single Season of High School Football.
Exploring resilience models in a sample of combat-exposed military service members and veterans: a comparison and commentaryRead Full Text
Brain Structural Covariance Network Topology in Remitted Posttraumatic Stress Disorder.
Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls.
A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder.
Sleep quality in returning veterans: The influence of mild traumatic brain injury.
Self-Reported Pain in Male and Female Iraq/Afghanistan-Era Veterans: Associations with Psychiatric Symptoms and Functioning.
The Post-Deployment Mental Health (PDMH) study and repository: A multi-site study of US Afghanistan and Iraq era veterans.
Practices and outcomes of self-treatment with helminths based on physicians' observations.
ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide.
Inter-site and inter-scanner diffusion MRI data harmonization.
Sexual revictimization among Iraq and Afghanistan war era veterans.
Genome-Wide Association of Neuroimaging Phenotypes in PTSD at Multiple SitesRead Full Text
Neurosteroids and traumatic brain injury translating biomarkers to therapeutics; overview and pilot investigations in Iraq and Afghanistan era veteransRead Full Text
Amygdala, Hippocampus, and Ventral Medial Prefrontal Cortex Volumes Differ in Maltreated Youth with and without Chronic Posttraumatic Stress Disorder.
Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.
Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder.
Functional correlates of military sexual assault in male veterans.
The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration.
Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder.
Trauma re-experiencing symptoms modulate topology of intrinsic functional networks.
Drug use and childhood-, military- and post-military trauma exposure among women and men veterans.
Assessment of Myelin Compromise in Mild Traumatic Brain Injury with Quantitative Susceptibility MappingRead Full Text
Amygdala-prefrontal cortex functional connectivity during threat-induced anxiety and goal distraction.
White matter compromise in veterans exposed to primary blast forces.
Neuroimaging assessment of early and late neurobiological sequelae of traumatic brain injury: implications for CTE.
The factor structure of psychiatric comorbidity among Iraq/Afghanistan-era veterans and its relationship to violence, incarceration, suicide attempts, and suicidality.
DSM-5 posttraumatic stress disorder: factor structure and rates of diagnosis.
No association between RORA polymorphisms and PTSD in two independent samples.
Examining the factor structure of the Connor-Davidson Resilience Scale (CD-RISC) in a post-9/11 U.S. military veteran sample.
The impact of social support on psychological distress for U.S. Afghanistan/Iraq era veterans with PTSD and other psychiatric diagnoses.
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
Amino acids as biomarker candidates for suicidality in male OEF/OIF Veterans: relevance to NMDA receptor modulation and nitric oxide signaling.
Acute effects of trauma-focused research procedures on participant safety and distress.
Altered resting-state functional connectivity of basolateral and centromedial amygdala complexes in posttraumatic stress disorder.
Effects of chronic mild traumatic brain injury on white matter integrity in Iraq and Afghanistan war veterans.
The association of sleep duration, mental health, and health risk behaviors among U.S. Afghanistan/Iraq era veteransRead Full Text
Network Analysis of Intrinsic Functional Organization of the Brain in Mild Traumatic Brain InjuryRead Full Text
Vulnerability or Consequence: Amygdala Volume Changes with PTSD in a Large Case-Controlled Veteran GroupRead Full Text
Diffusion Tensor Imaging of OEF/OIF Veterans with and without Exposure to Primary Blast ForcesRead Full Text
Amygdala volume changes in posttraumatic stress disorder in a large case-controlled veterans group.
A case of frontal neuropsychological and neuroimaging signs following multiple primary-blast exposure.
Resting State Connectivity Between Amygdalar Subregions and the Prefrontal Cortex is Disrupted in PTSDRead Full Text
Neural systems for guilt from actions affecting self versus others.
Brain imaging investigation of the impairing effect of emotion on cognition.
Neural systems for cognitive and emotional processing in posttraumatic stress disorder.
Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder.
Clinical Predictors of White Matter Disruption in Chronic Mild Traumatic Brain Injury among Post-9/11 VeteransRead Full Text
Reduced Amygdala and Hippocampal Volumes Associated with PTSD in Recent Military Veterans from Iraq and AfghanistanRead Full Text
Reduced hippocampal and amygdala activity predicts memory distortions for trauma reminders in combat-related PTSD.
Scan-rescan reliability of subcortical brain volumes derived from automated segmentation.
Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001.
Correlates of anger and hostility in Iraq and Afghanistan war veterans.
Staying cool when things get hot: emotion regulation modulates neural mechanisms of memory encoding.
Rebuttal to Hasan and Pedraza in comments and controversies: "Improving the reliability of manual and automated methods for hippocampal and amygdala volume measurements".
Association of trauma exposure with psychiatric morbidity in military veterans who have served since September 11, 2001.
The role of trauma-related distractors on neural systems for working memory and emotion processing in posttraumatic stress disorder.
A comparison of automated segmentation and manual tracing for quantifying hippocampal and amygdala volumes.
Alterations in the neural circuitry for emotion and attention associated with posttraumatic stress symptomatology.
The validity and diagnostic efficiency of the Davidson Trauma Scale in military veterans who have served since September 11th, 2001.
Alcohol use among OEF-OIF veterans with and without posttraumatic stress disorderRead Full Text
Factorial invariance of posttraumatic stress disorder symptoms across three veteran samples.
L-serine predicts self-reported pain in female OEF/OIF veteransRead Full Text
Trauma-related distractors modulate neural systems for working memory in posttraumatic stress disorderRead Full Text
Neural systems for executive and emotional processing are modulated by symptoms of posttraumatic stress disorder in Iraq War veterans.
Neural correlates of automatic and controlled auditory processing in schizophrenia.
Neuroactive steroids are related to psychiatric symptoms in veterans returning from iraq and AfghanistanRead Full Text
Neural systems for executive and emotional processing are modulated by level of posttraumatic stress disorder symptoms in Iraq war veteransRead Full Text
Functional magnetic resonance imaging measure of automatic and controlled auditory processing.
Disrupted task related activation to action selection and conflict resolution in patients with schizophreniaRead Full Text
Imaging frontostriatal function in ultra-high-risk, early, and chronic schizophrenia during executive processing.
Functional MRI assessment of atypical and conventional antipsychotic effects on cognitive function in schizophrenia patientsRead Full Text