Faculty

Rajendra Morey

Associate Professor of Psychiatry and Behavioral Sciences

Psychiatry & Behavioral Sciences, Translational Neuroscience
School of Medicine

Faculty Network Member of the Duke Institute for Brain Sciences

Duke Institute for Brain Sciences
Institutes and Provost's Academic Units

Member of the Center for Brain Imaging and Analysis

Duke-UNC Center for Brain Imaging and Analysis
School of Medicine
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Box 3918 Med Ctr, Durham, NC 27710

Brain Imaging Analy Ctr, Hock Plaza, Room 5158, Durham, NC 27710

(919) 681-4994 rajendra.morey@duke.edu

Research in my lab is focused on brain changes associated with posttraumatic stress disorder (PTSD), traumatic brain injury (TBI), and other neuropsychiatric disorders. We apply several advanced methods for understanding brain function including functional MRI, structural MRI, diffusion tensor imaging, and genetic effects.


Education & Training

B.S. 1985

Case Western Reserve University

M.S. 1992

Case Western Reserve University

M.D. 1997

Drexel University

Grants

IPA - Mary Nicole Buckley

IPA - Delin Sun

Trauma and Genomics Modulate Brain Structure across Common Psychiatric Disorders

National Institutes of Health

IPA - Ryan Wagner

White Matter Damage in Subconcussive Blast Exposure

National Institutes of Health

RAM Replay Clinical Outcomes for TBI/Suicidality Option

An Analysis of Psychosocial Risk and Protective Factors: Accelerated Cognitive Aging and Mild Traumatic Brain Injury (MTBI) Among Retired NFL & Former NCAA Football Players

The George Washington University

IPA - Emily Clarke

ENIGMA-SD: Understanding Sex Differences in Global Mental Health through ENIGMA

University of Southern California

IPA - Rachel Phillips

An Analysis of Psychosocial Risk and Protective Factors: Accelerated Cognitive Aging and Mild Traumatic Brain Injury (MTBI) Among Retired NFL & Former NCAA Football Players

National Institutes of Health

IPA - Delin Sun

IPA - Chelsea Swanson

A Compute Cluster for Brain Imaging and Analysis

National Institutes of Health

IPA - Nan-Kuei Chen

IPA - Madeline Jacobs

IPA - Chunlei Liu

IPA-AVANI VORA

IPA - Kevin Labar

IPA - Kevin LaBar

Veterans Administration Medical Center

IPA - Chunlei Liu

Veterans Administration Medical Center

IPA-Shannon Beall

IPA - Shannon Beall

Veterans Administration Medical Center

PTSD-like phenotype of mice lacking GIT2

National Institutes of Health

FMRI Assessment of Attention and Memory in PTSD

National Institutes of Health

IPA - Courtney Haswell

Veterans Administration Medical Center

A Linux Cluster Computational Facility for Neuroimaging Research

National Institutes of Health

Neuroimaging of Trauma Memory and Cognitive Reappraisal in PTSD

National Institutes of Health
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Publications

The genetic architecture of the human cerebral cortex.

PMID 32193296
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Combat exposure, posttraumatic stress disorder, and head injuries differentially relate to alterations in cortical thickness in military Veterans.

PMID 31600766
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The role of the dentate gyrus in stress-related disorders.

PMID 31695166
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A Pilot Study of Neurocognitive Function and Brain Structures in Adolescents With Alcohol Use Disorders: Does Maltreatment History Matter?

PMID 30935216
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Resilience as a translational endpoint in the treatment of PTSD.

PMID 30867558
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Pain Intensity and Pain Interference in Male and Female Iraq/Afghanistan-era Veterans.

PMID 31253239
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Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder: A Mendelian Randomization Study.

PMID 31050786
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Brain structural covariance network centrality in maltreated youth with PTSD and in maltreated youth resilient to PTSD.

PMID 29633688
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Resting-state brain fluctuation and functional connectivity dissociate moral injury from posttraumatic stress disorder.

PMID 30690812
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Adaptive Identification of Cortical and Subcortical Imaging Markers of Early Life Stress and Posttraumatic Stress Disorder.

PMID 30714246
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Relationship between traumatic brain injury history and recent suicidal ideation in Iraq/Afghanistan-era veterans.

PMID 30382745
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108. Hippocampal Subfield Volumes Relate to Unique Phenotypes of PTSD: International Analysis by the PGC-ENIGMA PTSD Working Group

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Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry.

PMID 30699873
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Current progress and future direction in the genetics of PTSD: Focus on the development and contributions of the PGC-PTSD working group

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The association of resilience on psychiatric, substance use, and physical health outcomes in combat trauma-exposed military service members and veterans.

PMID 31263518
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Widespread Cortical Thickness Is Associated With Neuroactive Steroid Levels.

PMID 31798395
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Behavioral and Health Outcomes Associated With Deployment and Nondeployment Acquisition of Traumatic Brain Injury in Iraq and Afghanistan Veterans.

PMID 29859179
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Smaller hippocampal CA1 subfield volume in posttraumatic stress disorder.

PMID 30256497
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Informing Federal Policy on Firearm Restrictions for Veterans with Fiduciaries: Risk Indicators in the Post-Deployment Mental Health Study.

PMID 29797151
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The Association Between Alcohol Consumption, Lifetime Alcohol Use Disorder, and Psychiatric Distress Among Male and Female Veterans.

PMID 30079875
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White matter abnormalities in mild traumatic brain injury with and without post-traumatic stress disorder: a subject-specific diffusion tensor imaging study.

PMID 28676987
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ENIGMA military brain injury: A coordinated meta-analysis of diffusion MRI from multiple cohorts

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Genomic Approaches to Posttraumatic Stress Disorder: The Psychiatric Genomic Consortium Initiative.

PMID 29555185
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Risk factors for concurrent suicidal ideation and violent impulses in military veterans.

PMID 28627921
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Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.

PMID 28439101
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Structural covariance network centrality in maltreated youth with posttraumatic stress disorder.

PMID 29294430
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Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia.

PMID 29217296
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Multi-site harmonization of diffusion MRI data in a registration framework.

PMID 28176263
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White Matter Changes Related to Subconcussive Impact Frequency during a Single Season of High School Football.

PMID 29269405
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Exploring resilience models in a sample of combat-exposed military service members and veterans: a comparison and commentary

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Brain Structural Covariance Network Topology in Remitted Posttraumatic Stress Disorder.

PMID 29651256
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Genome-wide association study of subcortical brain volume in PTSD cases and trauma-exposed controls.

PMID 29187748
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A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder.

PMID 29178946
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Sleep quality in returning veterans: The influence of mild traumatic brain injury.

PMID 28703617
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Self-Reported Pain in Male and Female Iraq/Afghanistan-Era Veterans: Associations with Psychiatric Symptoms and Functioning.

PMID 28122941
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The Post-Deployment Mental Health (PDMH) study and repository: A multi-site study of US Afghanistan and Iraq era veterans.

PMID 28656593
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Practices and outcomes of self-treatment with helminths based on physicians' observations.

PMID 27240605
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ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide.

PMID 26658930
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Inter-site and inter-scanner diffusion MRI data harmonization.

PMID 27138209
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Sexual revictimization among Iraq and Afghanistan war era veterans.

PMID 27149409
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Genome-Wide Association of Neuroimaging Phenotypes in PTSD at Multiple Sites

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Neurosteroids and traumatic brain injury translating biomarkers to therapeutics; overview and pilot investigations in Iraq and Afghanistan era veterans

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Amygdala, Hippocampus, and Ventral Medial Prefrontal Cortex Volumes Differ in Maltreated Youth with and without Chronic Posttraumatic Stress Disorder.

PMID 26171720
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Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.

PMID 26176345
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Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder.

PMID 26670285
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Functional correlates of military sexual assault in male veterans.

PMID 26524280
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The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration.

PMID 25904361
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Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder.

PMID 26184988
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Trauma re-experiencing symptoms modulate topology of intrinsic functional networks.

PMID 26143974
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Drug use and childhood-, military- and post-military trauma exposure among women and men veterans.

PMID 25957156
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Assessment of Myelin Compromise in Mild Traumatic Brain Injury with Quantitative Susceptibility Mapping

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Amygdala-prefrontal cortex functional connectivity during threat-induced anxiety and goal distraction.

PMID 24882566
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White matter compromise in veterans exposed to primary blast forces.

PMID 24590156
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Neuroimaging assessment of early and late neurobiological sequelae of traumatic brain injury: implications for CTE.

PMID 26441507
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The factor structure of psychiatric comorbidity among Iraq/Afghanistan-era veterans and its relationship to violence, incarceration, suicide attempts, and suicidality.

PMID 25169889
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DSM-5 posttraumatic stress disorder: factor structure and rates of diagnosis.

PMID 25213835
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No association between RORA polymorphisms and PTSD in two independent samples.

PMID 25048002
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Examining the factor structure of the Connor-Davidson Resilience Scale (CD-RISC) in a post-9/11 U.S. military veteran sample.

PMID 24586090
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The impact of social support on psychological distress for U.S. Afghanistan/Iraq era veterans with PTSD and other psychiatric diagnoses.

PMID 24679515
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Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.

PMID 24038837
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Amino acids as biomarker candidates for suicidality in male OEF/OIF Veterans: relevance to NMDA receptor modulation and nitric oxide signaling.

PMID 24806493
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Acute effects of trauma-focused research procedures on participant safety and distress.

PMID 24262664
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Altered resting-state functional connectivity of basolateral and centromedial amygdala complexes in posttraumatic stress disorder.

PMID 23929546
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Effects of chronic mild traumatic brain injury on white matter integrity in Iraq and Afghanistan war veterans.

PMID 22706988
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The association of sleep duration, mental health, and health risk behaviors among U.S. Afghanistan/Iraq era veterans

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Network Analysis of Intrinsic Functional Organization of the Brain in Mild Traumatic Brain Injury

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Vulnerability or Consequence: Amygdala Volume Changes with PTSD in a Large Case-Controlled Veteran Group

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Diffusion Tensor Imaging of OEF/OIF Veterans with and without Exposure to Primary Blast Forces

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Amygdala volume changes in posttraumatic stress disorder in a large case-controlled veterans group.

PMID 23117638
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A case of frontal neuropsychological and neuroimaging signs following multiple primary-blast exposure.

PMID 21879996
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Resting State Connectivity Between Amygdalar Subregions and the Prefrontal Cortex is Disrupted in PTSD

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Neural systems for guilt from actions affecting self versus others.

PMID 22230947
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Brain imaging investigation of the impairing effect of emotion on cognition.

PMID 22330776
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Neural systems for cognitive and emotional processing in posttraumatic stress disorder.

PMID 23162499
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Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder.

PMID 21545724
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Clinical Predictors of White Matter Disruption in Chronic Mild Traumatic Brain Injury among Post-9/11 Veterans

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Reduced Amygdala and Hippocampal Volumes Associated with PTSD in Recent Military Veterans from Iraq and Afghanistan

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Reduced hippocampal and amygdala activity predicts memory distortions for trauma reminders in combat-related PTSD.

PMID 21047644
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Scan-rescan reliability of subcortical brain volumes derived from automated segmentation.

PMID 20162602
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Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001.

PMID 20735755
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Correlates of anger and hostility in Iraq and Afghanistan war veterans.

PMID 20551162
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Staying cool when things get hot: emotion regulation modulates neural mechanisms of memory encoding.

PMID 21212840
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Rebuttal to Hasan and Pedraza in comments and controversies: "Improving the reliability of manual and automated methods for hippocampal and amygdala volume measurements".

PMID 19616634
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Association of trauma exposure with psychiatric morbidity in military veterans who have served since September 11, 2001.

PMID 19232639
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The role of trauma-related distractors on neural systems for working memory and emotion processing in posttraumatic stress disorder.

PMID 19091328
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A comparison of automated segmentation and manual tracing for quantifying hippocampal and amygdala volumes.

PMID 19162198
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Alterations in the neural circuitry for emotion and attention associated with posttraumatic stress symptomatology.

PMID 19237269
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The validity and diagnostic efficiency of the Davidson Trauma Scale in military veterans who have served since September 11th, 2001.

PMID 18783913
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Alcohol use among OEF-OIF veterans with and without posttraumatic stress disorder

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Factorial invariance of posttraumatic stress disorder symptoms across three veteran samples.

PMID 18553409
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L-serine predicts self-reported pain in female OEF/OIF veterans

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Trauma-related distractors modulate neural systems for working memory in posttraumatic stress disorder

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Neural systems for executive and emotional processing are modulated by symptoms of posttraumatic stress disorder in Iraq War veterans.

PMID 18093809
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Neural correlates of automatic and controlled auditory processing in schizophrenia.

PMID 19196926
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Neuroactive steroids are related to psychiatric symptoms in veterans returning from iraq and Afghanistan

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Neural systems for executive and emotional processing are modulated by level of posttraumatic stress disorder symptoms in Iraq war veterans

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Functional magnetic resonance imaging measure of automatic and controlled auditory processing.

PMID 15770151
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Disrupted task related activation to action selection and conflict resolution in patients with schizophrenia

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Imaging frontostriatal function in ultra-high-risk, early, and chronic schizophrenia during executive processing.

PMID 15753238
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Functional MRI assessment of atypical and conventional antipsychotic effects on cognitive function in schizophrenia patients

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