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Redford B. Williams Jr., MD

Professor of Psychiatry and Behavioral Sciences
Professor of Medicine
Division: 
Behavioral Medicine
Category: 
Office: 905 W. Main Street, Suite 22 (2nd Floor), Durham, NC 27701
Campus Mail: DUMC Box 3926 Med Ctr, Durham, NC 27710

My research aims to identify psychosocial factors that are involved in the pathogenesis and course of major medical disorders, to characterize the biobehavioral mechanisms whereby such factors influence disease, and to develop both behavioral and pharmacologic means of preventing or ameliorating the adverse impact of psychosocial factors on health and disease. Specific projects that are currently active include: 1) The influence of hostile personality, social isolation, depression and other psychosocial risk factors upon the development and course of cardiometabolic disease; 2) Biological and genetic mechanisms whereby psychosocial risk factors influence disease development and course; and 3) Behavioral and pharmacologic approaches to ameliorate impact of psychosocial risk factors on disease risk and course.

Education and Training

  • M.D., Yale University, 1967

Selected Grants

Publications

Brummett, Beverly H., Christopher L. Muller, Ann L. Collins, Stephen H. Boyle, Cynthia M. Kuhn, Ilene C. Siegler, Redford B. Williams, Edward C. Suarez, and Allison Ashley-Koch. “Correction to: 5-HTTLPR and Gender Moderate Changes in Negative Affect Responses to Tryptophan Infusion.” Behav Genet 51, no. 2 (March 2021): 163. https://doi.org/10.1007/s10519-020-10030-y.

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Brummett, Beverly H., Stephen H. Boyle, Ilene C. Siegler, Cynthia M. Kuhn, Allison Ashley-Koch, Charles R. Jonassaint, Stephan Züchner, Ann Collins, Edward C. Suarez, and Redford B. Williams. “Correction to: Effects of Environmental Stress and Gender on Associations among Symptoms of Depression and the Serotonin Transporter Gene Linked Polymorphic Region (5-HTTLPR).” Behav Genet 51, no. 2 (March 2021): 162. https://doi.org/10.1007/s10519-020-10029-5.

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Schneiderman, Neil, Margaret A. Chesney, Redford B. Williams, Richard D. Lane, and Hans-Christian Deter. “A Tribute to Kristina Orth-Gomér - an Outstanding Scientist for Women's Health in Behavioral and Psychosomatic Medicine.” Psychosom Med 83, no. 2 (February 2021): 106–8. https://doi.org/10.1097/PSY.0000000000000906.

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Reavis, Zackery W., Nikhil Mirjankar, Srikant Sarangi, Stephen H. Boyle, Cynthia M. Kuhn, Wayne R. Matson, Michael A. Babyak, et al. “Sex and race differences of cerebrospinal fluid metabolites in healthy individuals.” Metabolomics 17, no. 2 (January 18, 2021): 13. https://doi.org/10.1007/s11306-020-01757-0.

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Jonassaint, Charles R., Ilene C. Siegler, John C. Barefoot, Christopher L. Edwards, Edward C. Suarez, and Redford B. Williams. “Correction to: Low Life Course Socioeconomic Status (SES) Is Associated with Negative NEO PI-R Personality Patterns.” Int J Behav Med 27, no. 6 (December 2020): 737. https://doi.org/10.1007/s12529-020-09923-3.

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Jiang, Rong, Michael A. Babyak, Beverly H. Brummett, Ilene C. Siegler, Cynthia M. Kuhn, and Redford B. Williams. “Corrigendum to "Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism interacts with gender to influence cortisol responses to mental stress" [Psychoneuroendocrinology 79 (2017) (May) 13-19].” Psychoneuroendocrinology 121 (November 2020): 104861. https://doi.org/10.1016/j.psyneuen.2020.104861.

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Singh, Abanish, Michael A. Babyak, Mario Sims, Solomon K. Musani, Beverly H. Brummett, Rong Jiang, William E. Kraus, et al. “Evaluating the precision of EBF1 SNP x stress interaction association: sex, race, and age differences in a big harmonized data set of 28,026 participants.” Transl Psychiatry 10, no. 1 (October 20, 2020): 351. https://doi.org/10.1038/s41398-020-01028-5.

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Meyer, Thomas, Isabel Rothe, Julia Staab, Hans-Christian Deter, Stella V. Fangauf, Stefanie Hamacher, Martin Hellmich, et al. “Length Polymorphisms in the Angiotensin I-Converting Enzyme Gene and the Serotonin-Transporter-Linked Polymorphic Region Constitute a Risk Haplotype for Depression in Patients with Coronary Artery Disease.” Biochem Genet 58, no. 4 (August 2020): 631–48. https://doi.org/10.1007/s10528-020-09967-w.

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Brummett, B. H., S. H. Boyle, C. M. Kuhn, I. C. Siegler, E. C. Suarez, and R. B. Williams. “Corrigendum to "Socioeconomic status moderates associations between CNS serotonin and expression of beta2-integrins CD11b and CD11c" [J. Psychiatr Res. (2010) 44:373-377].” J Psychiatr Res 126 (July 2020): 142. https://doi.org/10.1016/j.jpsychires.2019.11.003.

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Jiang, Rong, Kim M. Huffman, Elizabeth R. Hauser, Janet L. Huebner, Monica J. Hubal, Redford B. Williams, Ilene C. Siegler, and William E. Kraus. “The role of brain-derived neurotropic factor (BDNF) genetic variants in exercise training.” In Genetic Epidemiology, 44:491–92, 2020.

Scholars@Duke

Pages