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F Joseph McClernon, PhD

Professor in Psychiatry & Behavioral Sciences
Division: 
Addiction
Category: 
Office: 2608 Erwin Road, Suite 300, Durham, NC 27705
Campus Mail: DUMC 3527, Durham, NC 27710

Joe McClernon, Ph.D. is a Professor in the Department of Psychiatry and Behavioral Sciences, Founder/Director of the Center for Addiction Science and Technology (CfAST), and Director of Evaluation and Strategic Planning in the Duke Clinical and Translational Science Institute (CTSI). He earned a Ph.D. in clinical psychology in 2001 from Southern Illinois University-Carbondale and completed a postdoctoral fellowship at Duke in 2002. He served as Director of the Addiction Division in Psychiatry and Behavioral Sciences from 2012-2020. Joe’s research is focused on increasing our understanding of tobacco and other addictions, developing new and more effective interventions to treat substance abuse, and informing the FDA’s regulation of tobacco products. He makes use of behavioral pharmacology, neuroimaging, epidemiology and clinical trial approaches in his work. He has led groundbreaking research on: the influence of drug-associated environments on drug use, relapse, and treatment; tobacco use disparities among individuals with comorbid psychiatric (e.g. ADHD) and health (e.g. HIV) problems; the role of nicotine in smoking behavior; and the evaluation of potential FDA tobacco regulatory actions. He is an active mentor having trained six postdoctoral fellows, five of which are now faculty at academic medical centers across the country. He has been continuously NIH, FDA, and foundation funded since 2002. He has authored over 150 peer-reviewed publications, has one patent, has served as Chair of NIH grant review panels, and is recipient of numerous awards including the SRNT Jarvik-Russell New Investigator Award.

Education and Training

  • Ph.D., Southern Illinois University, 2001

Selected Grants

Publications

Pacek, Lauren R., Andrea C. Villanti, and F Joseph Mcclernon. “Not Quite the Rule, But No Longer the Exception: Multiple Tobacco Product Use and Implications for Treatment, Research, and Regulation.” Nicotine Tob Res 22, no. 11 (October 29, 2020): 2114–17. https://doi.org/10.1093/ntr/ntz221.

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Vilardaga, Roger, Javier Rizo, Paige E. Palenski, Paolo Mannelli, Jason A. Oliver, and Francis J. McClernon. “Erratum to: Pilot Randomized Controlled Trial of a Novel Smoking Cessation App Designed for Individuals With Co-Occurring Tobacco Dependence and Serious Mental Illness.” Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco, August 6, 2020. https://doi.org/10.1093/ntr/ntaa125.

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Vilardaga, Roger, Javier Rizo, Paige E. Palenski, Paolo Mannelli, Jason A. Oliver, and Francis J. Mcclernon. “Pilot Randomized Controlled Trial of a Novel Smoking Cessation App Designed for Individuals With Co-Occurring Tobacco Use Disorder and Serious Mental Illness.” Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco 22, no. 9 (August 2020): 1533–42. https://doi.org/10.1093/ntr/ntz202.

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Pacek, Lauren R., Alicia D. Holloway, Karen L. Cropsey, Christina S. Meade, Maggie M. Sweitzer, James M. Davis, and F Joseph McClernon. “Cigarette Smoking and Cessation-Related Interactions With Health Care Providers in the Context of Living With HIV: Focus Group Study Findings.” J Assoc Nurses Aids Care, July 2, 2020. https://doi.org/10.1097/JNC.0000000000000185.

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Robinson, Jason D., George Kypriotakis, Mustafa Al’absi, Rachel L. Denlinger-Apte, David J. Drobes, Scott J. Leischow, F Joseph McClernon, et al. “Very Low Nicotine Content Cigarettes Disrupt the Feedback Loop of Affective States and Smoking Behavior.” Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco 22, no. 8 (July 2020): 1294–1300. https://doi.org/10.1093/ntr/ntz209.

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Carroll, Dana Mowls, Lori Strayer, Natalie Nardone, Lauren R. Pacek, Rachel V. Kozink, Katelyn Tessier, Joseph McClernon, Neal Benowitz, Warren K. Bickel, and Dorothy Hatsukami. “Development and Piloting Testing of an Experimental Tobacco and Nicotine Product Marketplace.” Nicotine Tob Res 22, no. 7 (June 12, 2020): 1230–34. https://doi.org/10.1093/ntr/ntz195.

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Kollins, Scott H., Maggie M. Sweitzer, F Joseph McClernon, and Kenneth A. Perkins. “Increased subjective and reinforcing effects of initial nicotine exposure in young adults with attention deficit hyperactivity disorder (ADHD) compared to matched peers: results from an experimental model of first-time tobacco use.” Neuropsychopharmacology 45, no. 5 (April 2020): 851–56. https://doi.org/10.1038/s41386-019-0581-7.

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Carroll, Dana M., Sharon E. Murphy, Neal L. Benowitz, Andrew A. Strasser, Michael Kotlyar, Stephen S. Hecht, Steve G. Carmella, et al. “Relationships between the Nicotine Metabolite Ratio and a Panel of Exposure and Effect Biomarkers: Findings from Two Studies of U.S. Commercial Cigarette Smokers.” Cancer Epidemiol Biomarkers Prev 29, no. 4 (April 2020): 871–79. https://doi.org/10.1158/1055-9965.EPI-19-0644.

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Pacek, Lauren R., and F Joseph McClernon. “Risk perceptions regarding cigarette smoking in the United States continue to decline.” Drug and Alcohol Dependence 209 (April 2020): 107887. https://doi.org/10.1016/j.drugalcdep.2020.107887.

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Engelhard, Matthew M., Jason A. Oliver, and F Joseph McClernon. “Digital envirotyping: quantifying environmental determinants of health and behavior.” Npj Digit Med 3 (2020): 36. https://doi.org/10.1038/s41746-020-0245-3.

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