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Christina S. Meade, PhD

Associate Professor in Psychiatry and Behavioral Sciences
Associate Research Professor in the Department of Psychology and Neuroscience
Division: 
Behavioral Medicine & Neurosciences
Category: 
Office: 905 W. Main Street, Suite 24-E, Durham, NC 27701
Campus Mail: DUMC 905 W. Main Street, Box 102848, Durham, NC 27710

Dr. Meade’s domestic research program focuses on predictors of HIV risk behavior in adults with substance use and psychiatric disorders, and the relationship between neuropsychiatric conditions and continued risk behavior in HIV-positive adults. She is particularly interested in how drug addiction and HIV infection impact executive functions, such as decision making, that lead individuals to engage in risky behaviors. Many of her current projects incorporate MRI to isolate the effects of addiction and HIV on both brain function and structure. Dr. Meade is also interested in the development of evidence-based treatments to improve cognitive functioning and reduce risk behaviors among drug users.

Given that most people infected or affected by HIV/AIDS live in Sub-Saharan Africa, Dr. Meade’s international research program is based in South Africa. The Western Cape has experienced a dramatic increase in methamphetamine use since the early 2000s, and there is concern that it may further fuel the HIV epidemic in this country. Current projects focus on characterizing drug addiction and HIV risk behaviors in this understudied group, both in in community and treatment settings, and ultimately increasing uptake of HIV services to improve health outcomes and reduce the continued spread of HIV.

Education and Training

  • Ph.D., Yale University, 2006

Publications

Chen, Nan-Kuei, Ryan P. Bell, and Christina S. Meade. “On the down-sampling of diffusion MRI data along the angular dimension. (Accepted)” Magnetic Resonance Imaging 82 (October 2021): 104–10. https://doi.org/10.1016/j.mri.2021.06.012.

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Meade, Christina S., Xiang Li, Sheri L. Towe, Ryan P. Bell, Vince D. Calhoun, and Jing Sui. “Brain multimodal co-alterations related to delay discounting: a multimodal MRI fusion analysis in persons with and without cocaine use disorder.” Bmc Neurosci 22, no. 1 (August 20, 2021): 51. https://doi.org/10.1186/s12868-021-00654-z.

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Hall, Shana A., Ryan P. Bell, Simon W. Davis, Sheri L. Towe, Taylor P. Ikner, and Christina S. Meade. “Human immunodeficiency virus-related decreases in corpus callosal integrity and corresponding increases in functional connectivity.” Hum Brain Mapp, August 12, 2021. https://doi.org/10.1002/hbm.25592.

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Xu, Yunan, Sheri L. Towe, Shakiera T. Causey, and Christina S. Meade. “Using mobile health technologies to test the association of cocaine use with sexual desire and risky sexual behaviors among people with and without HIV who use illicit stimulants.” Drug Alcohol Depend 225 (August 1, 2021): 108744. https://doi.org/10.1016/j.drugalcdep.2021.108744.

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Tamargo, Javier A., Adriana Campa, Sabrina S. Martinez, Tan Li, Kenneth E. Sherman, Gustavo Zarini, Christina S. Meade, Raul N. Mandler, and Marianna K. Baum. “Cognitive Impairment among People Who Use Heroin and Fentanyl: Findings from the Miami Adult Studies on HIV (MASH) Cohort.” J Psychoactive Drugs 53, no. 3 (July 2021): 215–23. https://doi.org/10.1080/02791072.2020.1850946.

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Hall, Shana A., Sheri L. Towe, M Tauseef Nadeem, Andrea L. Hobkirk, Bennett W. Hartley, Rosa Li, Scott A. Huettel, and Christina S. Meade. “Hypoactivation in the precuneus and posterior cingulate cortex during ambiguous decision making in individuals with HIV.” Journal of Neurovirology 27, no. 3 (June 2021): 463–75. https://doi.org/10.1007/s13365-021-00981-1.

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Towe, Sheri L., Catherine A. Sullivan, Mehri S. McKellar, and Christina S. Meade. “Examining the Potential of Pre-exposure Prophylaxis (PrEP) for HIV Prevention in a Community Sample of Persons Who Use Stimulants Living in the Southern United States.” Aids Behav 25, no. 5 (May 2021): 1480–89. https://doi.org/10.1007/s10461-020-02987-y.

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Towe, Sheri L., Jeremiah T. Hartsock, Yunan Xu, and Christina S. Meade. “Web-Based Cognitive Training to Improve Working Memory in Persons with Co-Occurring HIV Infection and Cocaine Use Disorder: Outcomes from a Randomized Controlled Trial.” Aids Behav 25, no. 5 (May 2021): 1542–51. https://doi.org/10.1007/s10461-020-02993-0.

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Tamargo, Javier A., Christina S. Meade, Adriana Campa, Sabrina S. Martinez, Tan Li, Kenneth E. Sherman, and Marianna K. Baum. “Food Insecurity and Cognitive Impairment in the Miami Adult Studies on HIV (MASH) Cohort.” J Nutr 151, no. 4 (April 8, 2021): 979–86. https://doi.org/10.1093/jn/nxaa416.

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Pacek, Lauren R., Alicia D. Holloway, Karen L. Cropsey, Christina S. Meade, Maggie M. Sweitzer, James M. Davis, and F. Joseph McClernon. “Experiences With Smoking Cessation Attempts and Prior Use of Cessation Aids in Smokers With HIV: Findings From a Focus Group Study Conducted in Durham, North Carolina.” Aids Educ Prev 33, no. 2 (April 2021): 158–68. https://doi.org/10.1521/aeap.2021.33.2.158.

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