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Christina S. Meade, PhD

Associate Professor in Psychiatry and Behavioral Sciences
Associate Research Professor of Global Health
Associate Research Professor in the Department of Psychology and Neuroscience
Division: 
Addiction
Category: 
Office: 905 W. Main Street, Suite 24-E, Durham, NC 27701
Campus Mail: DUMC 905 W. Main Street, Box 102848, Durham, NC 27710

Dr. Meade’s domestic research program focuses on predictors of HIV risk behavior in adults with substance use and psychiatric disorders, and the relationship between neuropsychiatric conditions and continued risk behavior in HIV-positive adults. She is particularly interested in how drug addiction and HIV infection impact executive functions, such as decision making, that lead individuals to engage in risky behaviors. Many of her current projects incorporate MRI to isolate the effects of addiction and HIV on both brain function and structure. Dr. Meade is also interested in the development of evidence-based treatments to improve cognitive functioning and reduce risk behaviors among drug users.

Given that most people infected or affected by HIV/AIDS live in Sub-Saharan Africa, Dr. Meade’s international research program is based in South Africa. The Western Cape has experienced a dramatic increase in methamphetamine use since the early 2000s, and there is concern that it may further fuel the HIV epidemic in this country. Current projects focus on characterizing drug addiction and HIV risk behaviors in this understudied group, both in in community and treatment settings, and ultimately increasing uptake of HIV services to improve health outcomes and reduce the continued spread of HIV.

Education and Training

  • Ph.D., Yale University, 2006

Publications

Hall, Shana A., Zahra Lalee, Ryan P. Bell, Sheri L. Towe, and Christina S. Meade. “Synergistic effects of HIV and marijuana use on functional brain network organization.” Prog Neuropsychopharmacol Biol Psychiatry 104 (January 10, 2021): 110040. https://doi.org/10.1016/j.pnpbp.2020.110040.

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Lee, Jared, Ji-Young Lee, Christina S. Meade, Michael Cohn, Antonio Chahine, Samantha E. Dilworth, Jessica F. Magidson, Hetta Gouse, Dietmar Fuchs, and Adam W. Carrico. “Tryptophan degradation is associated with risk-taking propensity in methamphetamine users with treated HIV infection.” J Neurovirol 26, no. 5 (October 2020): 779–84. https://doi.org/10.1007/s13365-020-00841-4.

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Xu, Yunan, Sheri L. Towe, Shakiera T. Causey, Paul A. Dennis, and Christina S. Meade. “Effects of substance use on monetary delay discounting among people who use stimulants with and without HIV: An ecological momentary assessment study.” Exp Clin Psychopharmacol, August 6, 2020. https://doi.org/10.1037/pha0000423.

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Towe, Sheri L., Catherine A. Sullivan, Mehri S. McKellar, and Christina S. Meade. “Examining the Potential of Pre-exposure Prophylaxis (PrEP) for HIV Prevention in a Community Sample of Persons Who Use Stimulants Living in the Southern United States.” Aids Behav, August 5, 2020. https://doi.org/10.1007/s10461-020-02987-y.

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Towe, Sheri L., Jeremiah T. Hartsock, Yunan Xu, and Christina S. Meade. “Web-Based Cognitive Training to Improve Working Memory in Persons with Co-Occurring HIV Infection and Cocaine Use Disorder: Outcomes from a Randomized Controlled Trial.” Aids Behav, August 4, 2020. https://doi.org/10.1007/s10461-020-02993-0.

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Meade, Christina S., Sheri L. Towe, Yunan Xu, and Crissi Rainer. “HIV Prevalence and Associated Risks in a Respondent-Driven Sample of Illicit Stimulant Users in a Southern United States City.” Aids Behav 24, no. 8 (August 2020): 2336–46. https://doi.org/10.1007/s10461-020-02793-6.

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Bell, Ryan P., Sheri L. Towe, Zahra Lalee, Scott A. Huettel, and Christina S. Meade. “Neural sensitivity to risk in adults with co-occurring HIV infection and cocaine use disorder.” Cogn Affect Behav Neurosci 20, no. 4 (August 2020): 859–72. https://doi.org/10.3758/s13415-020-00806-4.

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Pacek, Lauren R., Alicia D. Holloway, Karen L. Cropsey, Christina S. Meade, Maggie M. Sweitzer, James M. Davis, and F Joseph McClernon. “Cigarette Smoking and Cessation-Related Interactions With Health Care Providers in the Context of Living With HIV: Focus Group Study Findings.” J Assoc Nurses Aids Care, July 2, 2020. https://doi.org/10.1097/JNC.0000000000000185.

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Towe, Sheri L., Christina S. Meade, Christine C. Cloak, Ryan P. Bell, Julian Baptiste, and Linda Chang. “Reciprocal Influences of HIV and Cannabinoids on the Brain and Cognitive Function.” J Neuroimmune Pharmacol, May 22, 2020. https://doi.org/10.1007/s11481-020-09921-y.

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Meade, Christina S., Ryan P. Bell, Sheri L. Towe, and Shana A. Hall. “Cocaine-related alterations in fronto-parietal gray matter volume correlate with trait and behavioral impulsivity.” Drug Alcohol Depend 206 (January 1, 2020): 107757. https://doi.org/10.1016/j.drugalcdep.2019.107757.

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