CSSPI Past Studies

Past Studies

Cognitive/Affective Mechanisms of Risk among Suicidal Adults with and without Substance Abuse (AFSP Distinguished Investigator Grant 0-134-11)

In this study of mechanisms of risk associated with suicidal behavior, we examined decision-making biases, psychophysiological patterns of response, and automatic affective responses to different types of stimulus cues among three groups of psychiatrically hospitalized adult patients with depression: (a) patients with no history of suicide attempts and no current substance abuse; (b) patients with suicide attempts but no substance abuse; and (c) patients with both suicide attempts and substance abuse. We examined the relationship of these mechanisms to post-discharge levels of suicidal thoughts.   

Impact of Adolescent Suicide Attempts on Parents (NIMH R01-MH081947) 

The study was designed to help us learn more about the impact of adolescent suicidal behavior and psychiatric hospitalization on families, and the needs of families working with suicidal youths. In this study, mothers of 144 teenagers who were hospitalized for suicide attempts and mothers of 144 teenagers who were hospitalized for other reasons participated in assessments at 1, 3, 6, and 12 months after hospital discharge. We are studying the treatment and support needs for mothers, the differences among mothers in their reactions to suicidal behavior, factors related to differences among families in how they cope with adolescent difficulties, and how differences among families are related to treatment participation and parenting after hospitalization. In two supplements to this study from NIMH, we are examining racial and ethnic differences among mothers in the impact of suicidal behavior, and the impact of suicidal behavior on fathers.

Post Admission Cognitive Therapy (PACT) for Treatment of Military Personnel with Suicidal Behaviors: A Multi-Site Randomized Trial (DOD Contract W81XWH-11-2-0106)

This study was a randomized controlled trial of an augmenting intensive cognitive behavioral intervention and follow-up care for military personnel who have been hospitalized following suicide attempts. Via subcontract from the Henry Jackson Foundation, Duke University has collaborated in the development of this study and provided follow-up assessments for military personnel who participated in this study.

Relapse Prevention for Suicidal Dually Diagnosed Youths (NIMH R34-MH67904)

An augmenting motivational interviewing and cognitive behavioral relapse prevention intervention (CBT-RP) for suicidal, depressed, and alcohol or substance abusing/dependent adolescents was developed, refined, and compared to treatment as usual in a pilot randomized controlled trial. There was preliminary evidence that youths receiving CBT-RP as an augmenting intervention had larger improvements in depressive symptoms and suicide ideation, and were less likely to need intensive intervention (e.g., hospitalization, day treatment, intensive outpatient care, residential treatment) relative to youths without the intervention.