Box 90999, Durham, NC 27708-0999
Center For Cognitive Neuroscie, Durham, NC 27708
Dr. Adcock received her undergraduate degree in psychology from Emory University and her MD and PhD in Neurobiology from Yale University. She completed her psychiatry residency training at Langley Porter Psychiatric Institute at UC-San Francisco and did neurosciences research as a postdoctoral fellow at UC-SF, the San Francisco VA Medical Center, and Stanford before joining the Duke faculty in 2007. Her work has been funded by NIDA, NIMH, NSF and Alfred P. Sloan and Klingenstein Fellowships in the Neurosciences, and the Brain & Behavior Research Foundation, and honored by NARSAD awards, the 2012 National Academy of Sciences Seymour Benzer Lectureship, and the 2015 ABAI BF Skinner Lectureship. The overall goals of her research program are to understand how brain systems for motivation support learning and to use mechanistic understanding of how behavior changes biology to meet the challenge of developing new therapies appropriate for early interventions for mental illness.
Large-Scale Network Topology Reveals Heterogeneity in Individuals With at Risk Mental State for Psychosis: Findings From the Longitudinal Youth-at-Risk Study.
Motivational valence alters memory formation without altering exploration of a real-life spatial environment.
Single session real-time fMRI neurofeedback has a lasting impact on cognitive behavioral therapy strategies.
Individual differences in regulatory focus predict neural response to reward.
Hippocampus and Prefrontal Cortex Predict Distinct Timescales of Activation in the Human Ventral Tegmental Area.
Distinct medial temporal lobe network states as neural contexts for motivated memory formationRead Full Text
Selectivity in Postencoding Connectivity with High-Level Visual Cortex Is Associated with Reward-Motivated Memory.
Selectivity in post-encoding connectivity with high-level visual cortex is associated with reward-motivated memory.
Distinct medial temporal networks encode surprise during motivation by reward versus punishment.
Disrupted salience network functional connectivity and white-matter microstructure in persons at risk for psychosis: findings from the LYRIKS study.
Cognitive Neurostimulation: Learning to Volitionally Sustain Ventral Tegmental Area Activation.
Hippocampal and Insular Response to Smoking-Related Environments: Neuroimaging Evidence for Drug-Context Effects in Nicotine Dependence.
Reward Anticipation Dynamics during Cognitive Control and Episodic Encoding: Implications for Dopamine.
Lack of Evidence for Regional Brain Volume or Cortical Thickness Abnormalities in Youths at Clinical High Risk for Psychosis: Findings From the Longitudinal Youth at Risk Study.
Resting state networks distinguish human ventral tegmental area from substantia nigra.
Enriched encoding: reward motivation organizes cortical networks for hippocampal detection of unexpected events.
ADHD, altered dopamine neurotransmission, and disrupted reinforcement processes: Implications for smoking and nicotine dependenceRead Full Text
ADHD, altered dopamine neurotransmission, and disrupted reinforcement processes: implications for smoking and nicotine dependence.
Altered striatal functional connectivity in subjects with an at-risk mental state for psychosis.
Mechanisms of motivation-cognition interaction: challenges and opportunities.
Context matters: the structure of task goals affects accuracy in multiple-target visual search.
Context matters: The structure of task goals affects accuracy in multiple-target visual searchRead Full Text
Mechanisms of motivation-cognition interaction: Challenges and opportunitiesRead Full Text
Preserved working memory and altered brain activation in persons at risk for psychosis.
Size matters: how age and reaching experiences shape infants' preferences for different sized objects.
Hippocampal networks habituate as novelty accumulates.
DOPAMINERGIC MODULATION OF REWARD-MOTIVATED MEMORYRead Full Text
THE ACTIVE AVOIDANCE OF THREAT ENHANCES NEURAL SENSITIVITY TO EXPECTANCY VIOLATION.Read Full Text
MOVE FASTER TO LEARN BETTER: EXPLORATION SPEED IMPACTS LEARNING ABOUT OBJECTS AND THEIR LOCATIONSRead Full Text
Threat of punishment motivates memory encoding via amygdala, not midbrain, interactions with the medial temporal lobe.
Midbrain Modulation of Hippocampus Dependent Learning in Singaporeans at Ultra High Risk for the Development of SchizophreniaRead Full Text
Dorsolateral prefrontal cortex drives mesolimbic dopaminergic regions to initiate motivated behavior.
Amygdala Reactivity in Singaporeans at Ultra High Risk for the Development of SchizophreniaRead Full Text
Electrophysiological and diffusion tensor imaging evidence of delayed corollary discharges in patients with schizophrenia.
Reprint of: fMRI studies of successful emotional memory encoding: a quantitative meta-analysis.
Is all motivation good for learning? Dissociable influences of approach and avoidance motivation in declarative memory.
fMRI studies of successful emotional memory encoding: A quantitative meta-analysis.
Dopamine and adaptive memory.
Generalized Enhancement of Episodic Memory by Prior Reward ExperienceRead Full Text
Functional significance of striatal responses during episodic decisions: recovery or goal attainment?
Timing is everything: Neural response dynamics during syllable processing and its relation to higher-order cognition in schizophrenia and healthy comparison subjects
When top-down meets bottom-up: auditory training enhances verbal memory in schizophrenia.
Activation in the VTA and nucleus accumbens increases in anticipation of both gains and losses.
Reward-motivated learning: mesolimbic activation precedes memory formation.
Remembrance of rewards past
Functional neuroanatomy of executive processes involved in dual-task performance.
Respiratory sinus arrhythmia and cardiovascular responses to stress.
Caffeine effects on cardiovascular and neuroendocrine responses to acute psychosocial stress and their relationship to level of habitual caffeine consumption.