Kathleen M. Hayden, PhD

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Associate Professor in Psychiatry and Behavioral Sciences
Department / Division:
Psychiatry / Geriatric Behavioral Health
Address:
Bryan Adrc
2200 W. Main St., Suite A-200
Durham, NC 27705
Office Telephone:
(919) 668-1584
Training:
  • PhD, Johns Hopkins University, 2004
Research Interests:
My research is focused on several areas with the central theme of early detection of cognitive changes and risk factors associated with the development of Alzheimer‘s disease (AD) and other dementias. Current areas of investigation are a) the epidemiology of cognitive decline and mild cognitive impairment due to AD, b) the study of cognitive endophenotypes, c) genetic risk factors for late onset AD, and d) the development of statistical methods to model cognitive profiles as they manifest at different stages of disease.
Representative Publications:
  • Hayden, KM; Welsh-Bohmer, KA. Epidemiology of cognitive aging and Alzheimer's disease: contributions of the cache county utah study of memory, health and aging. Current topics in behavioral neurosciences. 2012;10:3-31.  Abstract
  • Hayden, KM; Jones, RN; Zimmer, C; Plassman, BL; Browndyke, JN; Pieper, C; Warren, LH; Welsh-Bohmer, KA. Factor structure of the National Alzheimer's Coordinating Centers uniform dataset neuropsychological battery: an evaluation of invariance between and within groups over time. Alzheimer Disease and Associated Disorders. 2011;25:128-137.  Abstract
  • Hayden, KM; Reed, BR; Manly, JJ; Tommet, D; Pietrzak, RH; Chelune, GJ; Yang, FM; Revell, AJ; Bennett, DA; Jones, RN. Cognitive decline in the elderly: an analysis of population heterogeneity. Age and Ageing. 2011;40:684-689.  Abstract
  • Hayden, KM; Norton, MC; Darcey, D; Ostbye, T; Zandi, PP; Breitner, JC; Welsh-Bohmer, KA; Cache County Study Investigators. Occupational exposure to pesticides increases the risk of incident AD: the Cache County study. Neurology. 2010;74:1524-1530.  Abstract
  • Heinzen, EL; Need, AC; Hayden, KM; Chiba-Falek, O; Roses, AD; Strittmatter, WJ; Burke, JR; Hulette, CM; Welsh-Bohmer, KA; Goldstein, DB. Genome-wide scan of copy number variation in late-onset Alzheimer's disease. Journal of Alzheimer's Disease. 2010;19:69-77.  Abstract
  • Hayden, KM; Zandi, PP; West, NA; Tschanz, JT; Norton, MC; Corcoran, C; Breitner, JC; Welsh-Bohmer, KA; Cache County Study Group. Effects of family history and apolipoprotein E epsilon4 status on cognitive decline in the absence of Alzheimer dementia: the Cache County Study. Archives of Neurology. 2009;66:1378-1383.  Abstract
  • Rosenberg, PB; Mielke, MM; Tschanz, J; Cook, L; Corcoran, C; Hayden, KM; Norton, M; Rabins, PV; Green, RC; Welsh-Bohmer, KA; Breitner, JC; Munger, R; Lyketsos, CG. Effects of cardiovascular medications on rate of functional decline in Alzheimer disease. American Journal of Geriatric Psychiatry. 2008;16:883-892.  Abstract
  • Hayden, KM; Welsh-Bohmer, KA; Wengreen, HJ; Zandi, PP; Lyketsos, CG; Breitner, JC; Cache County Investigators. Risk of mortality with vitamin E supplements: the Cache County study. American Journal of Medicine. 2007;120:180-184.  Abstract
  • Hayden, KM; Zandi, PP; Khachaturian, AS; Szekely, CA; Fotuhi, M; Norton, MC; Tschanz, JT; Pieper, CF; Corcoran, C; Lyketsos, CG; Breitner, JC; Welsh-Bohmer, KA; Cache County Investigators. Does NSAID use modify cognitive trajectories in the elderly? The Cache County study. Neurology. 2007;69:275-282.  Abstract
  • Mielke, MM; Rosenberg, PB; Tschanz, J; Cook, L; Corcoran, C; Hayden, KM; Norton, M; Rabins, PV; Green, RC; Welsh-Bohmer, KA; Breitner, JC; Munger, R; Lyketsos, CG. Vascular factors predict rate of progression in Alzheimer disease. Neurology. 2007;69:1850-1858.  Abstract
  • Wengreen, HJ; Munger, RG; Corcoran, CD; Zandi, P; Hayden, KM; Fotuhi, M; Skoog, I; Norton, MC; Tschanz, J; Breitner, JC; Welsh-Bohmer, KA. Antioxidant intake and cognitive function of elderly men and women: the Cache County Study. Journal of Nutrition, Health and Aging. 2007;11:230-237.  Abstract
  • Hayden, KM; Zandi, PP; Lyketsos, CG; Khachaturian, AS; Bastian, LA; Charoonruk, G; Tschanz, JT; Norton, MC; Pieper, CF; Munger, RG; Breitner, JC; Welsh-Bohmer, KA; Cache County Investigators. Vascular risk factors for incident Alzheimer disease and vascular dementia: the Cache County study. Alzheimer Disease and Associated Disorders. 2006;20:93-100.  Abstract
  • Khachaturian, AS; Zandi, PP; Lyketsos, CG; Hayden, KM; Skoog, I; Norton, MC; Tschanz, JT; Mayer, LS; Welsh-Bohmer, KA; Breitner, JC. Antihypertensive medication use and incident Alzheimer disease: the Cache County Study. Archives of Neurology. 2006;63:686-692.  Abstract
  • Tschanz, JT; Welsh-Bohmer, KA; Lyketsos, CG; Corcoran, C; Green, RC; Hayden, K; Norton, MC; Zandi, PP; Toone, L; West, NA; Breitner, JC; Cache County Investigators. Conversion to dementia from mild cognitive disorder: the Cache County Study. Neurology. 2006;67:229-234.  Abstract
  • Hayden, KM; Warren, LH; Pieper, CF; Østbye, T; Tschanz, JT; Norton, MC; Breitner, JC; Welsh-Bohmer, KA. Identification of VaD and AD prodromes: the Cache County Study. Alzheimer's and Dementia. 2005;1:19-29.  Abstract
  • Hayden, KM; Zandi, PP; Lyketsos, CG; Tschanz, JT; Norton, MC; Khachaturian, AS; Pieper, CF; Welsh-Bohmer, KA; Breitner, JC; Cache County Investigators. Apolipoprotein E genotype and mortality: findings from the Cache County Study. Journal of the American Geriatrics Society. 2005;53:935-942.  Abstract
  • Hayden, KM; Pieper, CF; Welsh-Bohmer, KA; Breitner, JC; Norton, MC; Munger, R. Self- or proxy-reported stroke and the risk of Alzheimer disease. Archives of Neurology. 2004;61:982.  Abstract
  • Hayden, KM; Khachaturian, AS; Tschanz, JT; Corcoran, C; Nortond, M; Breitner, JC; Cache County Study Group. Characteristics of a two-stage screen for incident dementia. Journal of Clinical Epidemiology. 2003;56:1038-1045.  Abstract
  • Zandi, PP; Anthony, JC; Hayden, KM; Mehta, K; Mayer, L; Breitner, JC; Cache County Study Investigators. Reduced incidence of AD with NSAID but not H2 receptor antagonists: the Cache County Study. Neurology. 2002;59:880-886.  Abstract