Francis Joseph McClernon, PhD

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Professor in Psychiatry & Behavioral Sciences
Department / Division:
Psychiatry / Addictions
Address:
DUMC 3527
Durham, NC 27710
Office Telephone:
919-668-3987
Training:
  • PhD, Southern Illinois University-Carbondale, 2001
Residency:
  • Internship, Psychology, Medical University of South Carolina, 2000-2001
Fellowship:
  • Postdoctoral Fellow, Duke University Medical Center/Durham Veterans Administration Medical Center (North Carolina), 2001-2002
Clinical Interests:
Addiction research and treatment
Representative Publications:
  • McClernon, FJ; Conklin, CA; Kozink, RV; Adcock, RA; Sweitzer, MM; Addicott, MA; Chou, YH; Chen, NK; Hallyburton, MB; DeVito, AM. Hippocampal and Insular Response to Smoking-Related Environments: Neuroimaging Evidence for Drug-Context Effects in Nicotine Dependence. Neuropsychopharmacology (Nature). 2016;41:877-885.  Abstract
  • McClernon, FJ; Froeliger, B; Rose, JE; Kozink, RV; Addicott, MA; Sweitzer, MM; Westman, EC; Van Wert, DM. The effects of nicotine and non-nicotine smoking factors on working memory and associated brain function. Addiction Biology. 2016;21:954-961.  Abstract
  • Addicott, MA; Sweitzer, MM; Froeliger, B; Rose, JE; McClernon, FJ. Increased Functional Connectivity in an Insula-Based Network is Associated with Improved Smoking Cessation Outcomes. Neuropsychopharmacology (Nature). 2015;40:2648-2656.  Abstract
  • Donny, EC; Denlinger, RL; Tidey, JW; Koopmeiners, JS; Benowitz, NL; Vandrey, RG; al'Absi, M; Carmella, SG; Cinciripini, PM; Dermody, SS; Drobes, DJ; Hecht, SS; Jensen, J; Lane, T; Le, CT; McClernon, FJ; Montoya, ID; Murphy, SE; Robinson, JD; Stitzer, ML; Strasser, AA; Tindle, H; Hatsukami, DK. Randomized Trial of Reduced-Nicotine Standards for Cigarettes. The New England journal of medicine. 2015;373:1340-1349.  Abstract
  • McClernon, FJ; Addicott, MA; Sweitzer, MM. Smoking abstinence and neurocognition: implications for cessation and relapse. Current Topics in Behavioral Neurosciences. 2015;23:193-227.  Abstract
  • Addicott, MA; Froeliger, B; Kozink, RV; Van Wert, DM; Westman, EC; Rose, JE; McClernon, FJ. Nicotine and non-nicotine smoking factors differentially modulate craving, withdrawal and cerebral blood flow as measured with arterial spin labeling. Neuropsychopharmacology (Nature). 2014;39:2750-2759.  Abstract
  • Addicott, MA; Froeliger, B; Kozink, RV; Wert, DMV; Westman, EC; Rose, JE; McClernon, FJ. Nicotine and non-nicotine smoking factors differentially modulate craving, withdrawal and cerebral blood flow as measured with arterial spin labeling. Neuropsychopharmacology (Nature). 2014;39:2750-2759.  
  • Mitchell, JT; Schick, RS; Hallyburton, M; Dennis, MF; Kollins, SH; Beckham, JC; McClernon, FJ. Combined ecological momentary assessment and global positioning system tracking to assess smoking behavior: a proof of concept study. Journal of Dual Diagnosis. 2014;10:19-29.  Abstract
  • McClernon, FJ; Roy Choudhury, R. I am your smartphone, and I know you are about to smoke: the application of mobile sensing and computing approaches to smoking research and treatment. Nicotine and Tobacco Research (OUP). 2013;15:1651-1654.  Abstract
  • Froeliger, B; Kozink, RV; Rose, JE; Behm, FM; Salley, AN; McClernon, FJ. Hippocampal and striatal gray matter volume are associated with a smoking cessation treatment outcome: results of an exploratory voxel-based morphometric analysis. Psychopharmacology. 2010;210:577-583.  Abstract
  • Kozink, RV; Kollins, SH; McClernon, FJ. Smoking withdrawal modulates right inferior frontal cortex but not presupplementary motor area activation during inhibitory control. Neuropsychopharmacology. 2010;35:2600-2606.  Abstract
  • Kozink, RV; Lutz, AM; Rose, JE; Froeliger, B; McClernon, FJ. Smoking withdrawal shifts the spatiotemporal dynamics of neurocognition. Addiction Biology. 2010;15:480-490.  Abstract
  • McClernon, FJ. Neuroimaging of Nicotine Dependence: Key Findings and Application to the Study of Smoking-Mental Illness Comorbidity. Journal of Dual Diagnosis. 2009;5:168-178.  Abstract
  • McClernon, FJ; Kozink, RV; Lutz, AM; Rose, JE. 24-h smoking abstinence potentiates fMRI-BOLD activation to smoking cues in cerebral cortex and dorsal striatum. Psychopharmacology. 2009;204:25-35.  Abstract