The Division of Clinical Translational Neuroscience is focused on 1) Discovery Research to uncover disease mechanisms, novel biomarkers, and candidate treatments of CNS disorders; and 2) Clinical Research for translating high impact discoveries from the laboratory to the bedside.

Over the past 30 years, this Division has been involved with the development of many of the most successful diagnostic and therapeutic products used in neuropsychiatry today. For example, the Division was involved with the Phase 1, Phase 2 and Phase 3 studies of Amyvid^TM, the first FDA approved PET scan molecular imaging diagnostic aid for detecting brain amyloid plaques in Alzheimer’s diseas.

Upper images show an Alzheimer’s patient, compared to normal control in lower images.

Research Programs

Center for Pharmacometabolomics

Traumatic Stress and Health Research Lab

Neuropsychiatric Imaging Research Lab

Dzirasa Lab - Laboratory for Psychiatric Neuroengineering

Mouse Behavioral Neuroendophenotyping Core

Levin Lab

Neurosteroid Core

Schizophrenia Research Group

McEvoy Clinical Research Group

Affiliated Programs

Brain Imaging and Analysis Center (BIAC)

Center for Cognitive Neuroscience (CCN)

Mental Illness Research Education and Clinical Center (MIRECC)

Duke Clinical Research Institute Neurosciences Medicine Group