Division on Addiction Research and Translation


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At the Duke Addiction Division our aim is to promote discovery of the causes, consequences and treatments of addictive behavior, and to translate this knowledge in ways that improve the health of individuals, families and our community.

Clinical Providers:

Duke Addictions Program provides comprehensive evaluation, pharmaco and
behavioral therapy, and family and couples’ therapy. Clinicians in the DAP provide consult and oversight services at Lincoln Community Center, Duke Regional Hospital, and TROSA. This clinic also contributes to clinical trials and research on integrating substance abuse interventions into primary care. 
(919) 684-3850
Faculty: Patkar, Mannelli, Peindl

Duke Family Care Program serves underserved and adjudicated pregnant and parenting women through intensive home visiting and community-outreach based programming.
Faculty: McCoy
Duke Family Care Program

VA Substance Abuse Clinic serves the Veteran population with pharmaco- and behavioral therapy for smoking cessation and treatment of alcoholism and other substance abuse.
Faculty: Stein, McNiel, Moore

Duke Psychiatry Specialty Clinic of Cary combines the latest assessment and diagnostic techniques with comprehensive psychopharmacologic treatment options for alcoholism, substance abuse and other psychiatric
disorders for children, adolescents, and adults. Clinical services are offered in a private, office-park setting.
(919) 238-0008
Faculty: Patkar, Manelli

Research Programs 

Duke Center for Smoking Cessation is a multidisciplinary, multisite center working to elucidate the biological mechanisms underlying tobacco addiction and to promote the development of more effective smoking cessation treatments.
Faculty: Rose, Mukhin, Murugesan, Zuo, McClernon

McClernon Lab/Triangle Smoking Studies investigates the neural and behavioral bases of tobacco use and other addictive behaviors, the comorbidity between addiction and mental illness, and the development of novel technologies to improve treatment outcomes. The public face of the lab—Triangle Smoking Studies—recruits smokers from the Triangle area to participate in research.
Faculty: McClernon, Addicott, Kollins

HIV and Addictions Research Program (HARP) seeks to understand and develop interventions, both locally and globally, to improve HIV-related health outcomes among persons who use cocaine, methamphetamine, and marijuana. Research focuses on the neuropsychiatric basis of health risk behaviors among vulnerable populations, integrating neuroimaging and behavioral assessment strategies, with projects in the United States and South Africa.
Faculty: Meade

Levin Lab conducts research concerning the neurobehavioral bases of cognitive, emotional and addictive function in animal models. Research is focused on understanding the functional interactions of cholinergic systems with other brain areas and systems.
Faculty: Levin, Rezvani

Kollins Lab seeks to understand the behavioral, neuropharmacological, and genetic basis of smoking among individuals with Attention Deficit Hyperactivity Disorder (ADHD) using human laboratory psychopharmacology studies. The Kollins lab also explores the effects of secondhand smoke exposure on neurodevelopment and evaluates new pharmacological and non-pharmacological treatments for children and adults with ADHD.
Faculty: Kollins, Mitchell, McClernon

VA Alcohol Research Group uses preclinical neurophysiological and behavioral methods to understand the neural basis of substance abuse. The lab is particularly interested in adolescence as a neurologically and psychosocially significant phase for the initiation of and sensitivity to drug use.
Faculty: Swartzwelder, Moore, Fleming, Li

Kuhn Lab seeks to understand the interaction of hormonal and neural mechanisms that increase sensitivity to drug abuse and depression in adolescents and females. The lab takes a multidisciplinary approach which includes studying the behavioral response of rats to addictive drugs, the effects of gonadal steroids and other hormones on
dopamine neuron function, and the activation of neural circuits by rewarding and aversive stimuli.
Faculty: Kuhn, Schramm-Sapyta


Duke Addictions Program (DAP) and Substance Abuse Consult Liaison Program

Duke Center for Smoking Cessation

Duke Health Behavior Neuroscience Research Program

Levin Lab

Swartzwelder Group

Tong Lee Lab